Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.43 |
| ▸ | F2RL3 | Q96RI0 | 5/20 | 0.42 |
| ▸ | TNF | P01375 | 1/20 | 0.42 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.41 |
| ▸ | ELANE | P08246 | 1/20 | 0.41 |
| ▸ | PRTN3 | P24158 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL425218 | 0.76 | PAX8 (0.51) | TP53MAPTPAX8F2RL3TNF | |
| SCHEMBL27967549 | 0.73 | SLC16A3 (0.38) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL27967560 | 0.69 | — | — | |
| SCHEMBL27967473 | 0.68 | FGFR3 (0.33) | MAPTNPC1RAB9AALDH1A1L3MBTL1 | |
| SCHEMBL11985493 | 0.67 | MAPT (0.71) | TP53MAPTTNFNOD1NPC1 | |
| SCHEMBL421740 | 0.67 | PAX8 (0.49) | TP53MAPTPAX8F2RL3TNF | |
| SCHEMBL27910767 | 0.67 | ASIC3 (0.37) | ALDH1A1 | |
| SCHEMBL827403 | 0.65 | RAB9A (0.67) | TP53MAPTPAX8TNFNOD1 | |
| SCHEMBL13077892 | 0.64 | ALDH1A1 (0.65) | TP53MAPTNPC1RAB9AALDH1A1 | |
| Hydrogen Sulfide SCHEMBL16859912 | 0.63 | RAB9A (0.64) | TP53MAPTPAX8TNFNOD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102015637-B | Phenylpyrrole derivatives | DAIICHI SANKYO CO LTD | 2014-05-21 | — | — | CN | disclosed |