Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.44 |
| ▸ | RAB9A | P51151 | 6/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | MITF | O75030 | 1/20 | 0.42 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | XBP1 | P17861 | 1/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8765022 | 0.80 | HIF1A (0.58) | NPC1RAB9AMEN1KMT2AHIF1A | |
| SCHEMBL4837127 | 0.80 | ALDH1A1 (0.50) | NPC1RAB9AMEN1KMT2AHIF1A | |
| SCHEMBL8765028 | 0.74 | HIF1A (0.55) | NPC1RAB9AMEN1KMT2AHIF1A | |
| SCHEMBL27968340 | 0.73 | GAA (0.51) | NPC1RAB9AMEN1KMT2AHIF1A | |
| SCHEMBL1568047 | 0.71 | SMO (0.57) | NPC1RAB9AMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL5907330 | 0.70 | HIF1A (0.53) | NPC1RAB9AMEN1KMT2AHIF1A | |
| SCHEMBL29042745 | 0.69 | MPO (0.49) | MEN1KMT2AMAPTALDH1A1HTT | |
| SCHEMBL6534028 | 0.69 | NR4A3 (0.65) | NPC1RAB9AMAPTALDH1A1HTT | |
| SCHEMBL11400405 | 0.69 | MEN1 (0.52) | NPC1RAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL5907288 | 0.68 | PTGS2 (0.36) | NPC1RAB9AMEN1KMT2AS1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103819465-A | Novel compound | MITSUBISHI TANABE PHARMA CORP | 2014-05-28 | — | — | CN | disclosed |