Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.85 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.85 |
| ▸ | IDO1 | P14902 | 3/20 | 0.85 |
| ▸ | HPGD | P15428 | 2/20 | 0.85 |
| ▸ | TTK | P33981 | 2/20 | 0.85 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.85 |
| ▸ | GAA | P10253 | 2/20 | 0.85 |
| ▸ | ALPL | P05186 | 1/20 | 0.85 |
| ▸ | NPC1 | O15118 | 1/20 | 0.66 |
| ▸ | TP53 | P04637 | 1/20 | 0.66 |
| ▸ | RAB9A | P51151 | 1/20 | 0.66 |
| ▸ | MAP2K4 | P45985 | 3/20 | 0.60 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.59 |
| ▸ | AURKA | O14965 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | MAPKAPK3 | Q16644 | 1/20 | 0.55 |
| ▸ | MAPK6 | Q16659 | 1/20 | 0.55 |
| ▸ | DCLK1 | O15075 | 1/20 | 0.54 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.54 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30768403 | 0.92 | ALDH1A1 (1.00) | ALDH1A1KDM4EIDO1HPGDTTK | |
| SCHEMBL855531 | 0.92 | ALDH1A1 (1.00) | ALDH1A1KDM4EIDO1HPGDTTK | |
| SCHEMBL17178615 | 0.88 | ALDH1A1 (0.92) | ALDH1A1KDM4EIDO1HPGDTTK | |
| SCHEMBL1672674 | 0.81 | IDO1 (0.78) | ALDH1A1KDM4EIDO1HPGDTTK | |
| SCHEMBL5377572 | 0.81 | ALDH1A1 (0.71) | ALDH1A1KDM4EIDO1HPGDTTK | |
| SCHEMBL18977088 | 0.79 | TTK (0.75) | ALDH1A1KDM4EIDO1HPGDTTK | |
| SCHEMBL10533662 | 0.78 | IDO1 (0.74) | ALDH1A1KDM4EIDO1HPGDTTK | |
| SCHEMBL19597646 | 0.78 | TTK (0.72) | ALDH1A1KDM4EIDO1HPGDTTK | |
| Propionic Acid SCHEMBL4552403 | 0.78 | KDM4E (0.71) | ALDH1A1KDM4EIDO1HPGDTTK | |
| SCHEMBL4480025 | 0.77 | ALDH1A1 (0.71) | ALDH1A1KDM4EIDO1HPGDTTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103980280-B | A kind of method of synthetic quinazolinone indazole derivative under acid condition | WENZHOU UNIVERSITY (CN) | 2016-05-04 | — | — | CN | disclosed |
| CN-103992325-B | A kind of synthetic method of N-phenyl indazole [3,2-b] quinazoline-7 (5H)-one derivative | WENZHOU UNIVERSITY (CN) | 2015-12-09 | — | — | CN | disclosed |
| CN-103664963-B | Method for synthesizing quinazolino indazole derivatives | UNIV WENZHOU | 2015-07-01 | — | — | CN | disclosed |
| CN-103992325-A | Method for synthesizing N-phenyl indazole [3,2-b] quinazoline-7(5H)-ketone derivatives | UNIV WENZHOU | 2014-08-20 | — | — | CN | disclosed |
| CN-103980280-A | Method for synthesizing quinazolino indazole derivatives under acidic condition | UNIV WENZHOU | 2014-08-13 | — | — | CN | disclosed |