Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.71 |
| ▸ | IDO1 | P14902 | 3/20 | 0.71 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.71 |
| ▸ | ALPL | P05186 | 1/20 | 0.71 |
| ▸ | GAA | P10253 | 1/20 | 0.71 |
| ▸ | HPGD | P15428 | 1/20 | 0.71 |
| ▸ | TTK | P33981 | 1/20 | 0.71 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.71 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.64 |
| ▸ | MEN1 | O00255 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.64 |
| ▸ | MAP2K4 | P45985 | 6/20 | 0.60 |
| ▸ | ITK | Q08881 | 4/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | MAPKAPK3 | Q16644 | 3/20 | 0.56 |
| ▸ | MAPK6 | Q16659 | 3/20 | 0.56 |
| ▸ | MAPKAPK2 | P49137 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17178615 | 0.84 | ALDH1A1 (0.92) | ALDH1A1IDO1KDM4EALPLGAA | |
| SCHEMBL855531 | 0.84 | ALDH1A1 (1.00) | ALDH1A1IDO1KDM4EALPLGAA | |
| SCHEMBL30768403 | 0.84 | ALDH1A1 (1.00) | ALDH1A1IDO1KDM4EALPLGAA | |
| SCHEMBL1672674 | 0.81 | IDO1 (0.78) | ALDH1A1IDO1KDM4EALPLGAA | |
| SCHEMBL4200287 | 0.81 | IDO1 (0.71) | ALDH1A1IDO1KDM4EALPLGAA | |
| SCHEMBL28982378 | 0.81 | IDO1 (0.71) | ALDH1A1IDO1KDM4EALPLGAA | |
| SCHEMBL5381079 | 0.81 | IDO1 (0.71) | ALDH1A1IDO1KDM4EALPLGAA | |
| SCHEMBL5377572 | 0.81 | ALDH1A1 (0.71) | ALDH1A1IDO1KDM4EALPLGAA | |
| SCHEMBL12318475 | 0.81 | KDM4E (0.71) | ALDH1A1IDO1KDM4EALPLGAA | |
| SCHEMBL4199525 | 0.80 | KDM4E (0.65) | ALDH1A1IDO1KDM4EALPLGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3688126-B1 | LUBRICATING OIL COMPOSITION FOR INTERNAL COMBUSTION ENGINE | SHELL INT RESEARCH (NL) | 2024-06-12 | — | — | EP | disclosed |
| EP-3397740-B1 | LUBRICATING OIL COMPOSITION FOR DIESEL ENGINES | SHELL INT RESEARCH (NL) | 2021-12-08 | — | — | EP | disclosed |
| US-20200263106-A1 | LUBRICATING OIL COMPOSITION FOR DIESEL ENGINES | SHELL OIL COMPANY | 2020-08-20 | — | — | US | disclosed |
| EP-3688126-A1 | LUBRICATING OIL COMPOSITION FOR INTERNAL COMBUSTION ENGINE | Shell Internationale Research Maatschappij B.V. (NL) | 2020-08-05 | — | — | EP | disclosed |
| US-20200224118-A1 | LUBRICATING OIL COMPOSITION FOR INTERNAL COMBUSTION ENGINE | SHELL OIL COMPANY | 2020-07-16 | — | — | US | disclosed |
| WO-2019063599-A1 | LUBRICATING OIL COMPOSITION FOR INTERNAL COMBUSTION ENGINE | SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. (NL) | 2019-04-04 | — | — | WO | disclosed |
| EP-3397740-A1 | LUBRICATING OIL COMPOSITION FOR DIESEL ENGINES | SHELL INTERNATIONAL RESEARCH MAATSCHAPPIJ B.V. (NL) | 2018-11-07 | — | — | EP | disclosed |
| US-9850276-B2 | Bidentate-binding modulators of LRRK2 and JNK kinases | THE SCRIPPS RESEARCH INSTITUTE (US) | 2017-12-26 | — | — | US | disclosed |
| WO-2017114836-A1 | LUBRICATING OIL COMPOSITION FOR DIESEL ENGINES | SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. (NL) | 2017-07-06 | — | — | WO | disclosed |
| US-20160185818-A1 | BIDENTATE-BINDING MODULATORS OF LRRK2 AND JNK KINASES | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED | 2016-06-30 | — | — | US | disclosed |
| EP-1425011-B1 | ENHANCEMENT OF LEARNING AND MEMORY AND TREATMENT OF AMNESIA | CARLSBAD TECHNOLOGY INC (US) | 2009-11-04 | — | — | EP | disclosed |
| US-7514465-B2 | Synthesis of N2-(substituted arylmethyl)-3-(substituted phenyl)indazoles as novel anti-angiogenic agents | YUNG SHIN PHARM. IND. CO., LTD. (TW) | 2009-04-07 | — | — | US | disclosed |
| US-7514465-B2 | Synthesis of N2-(substituted arylmethyl)-3-(substituted phenyl)indazoles as novel anti-angiogenic agents | YUNG SHIN PHARM. IND. CO., LTD. (TW) | 2009-04-07 | — | — | US | disclosed |
| EP-1331223-B1 | Method of treating sepsis | YUNG SHIN PHARMACEUTICAL IND (TW) | 2008-02-13 | — | — | EP | disclosed |
| EP-1659115-A1 | Synthesis of substituted 2H-indazole derivatives as anti-angiogenic agents | Yung Shin Pharm. Ind. Co., Ltd. (TW) | 2006-05-24 | — | — | EP | disclosed |
| US-20060106032-A1 | Synthesis of N2 - (substituted arylmethyl) -3- (substituted phenyl) indazoles as novel anti-angiogenic agents | YUNG SHIN PHARM. IND. CO., LTD. (TW) | 2006-05-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160185818-A1 | BIDENTATE-BINDING MODULATORS OF LRRK2 AND JNK KINASES | LRRK2, PINK1, MAP2K3 | ALDH1A1 4330/4885IDO1 2389/4885KDM4E 2312/4885 |
| US-20060106032-A1 | Synthesis of N2 - (substituted arylmethyl) -3- (substituted phenyl) indazoles as novel anti-angiogenic agents | FLT4, FLT1, KDR | ALDH1A1 851/4885IDO1 94/4885KDM4E 1210/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.