Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 3/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | PNMT | P11086 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CES1 | P23141 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA4 | P22748 | 1/20 | 0.37 |
| ▸ | CA6 | P23280 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27656924 | 0.82 | ALOX5 (0.41) | HTR7HTR1APNMTNPC1RAB9A | |
| SCHEMBL28115162 | 0.82 | PNMT (0.52) | HTR7HTR1APNMTNPC1RAB9A | |
| SCHEMBL27631807 | 0.80 | HTR1A (0.53) | HTR7HTR1AKDM4EMAPTSMN1; SMN2 | |
| SCHEMBL28897871 | 0.79 | HTR7 (0.42) | HTR7HTR1APNMTNPC1RAB9A | |
| SCHEMBL29249276 | 0.79 | ALDH1A1 (0.47) | HTR7HTR1APNMTNPC1RAB9A | |
| SCHEMBL5048009 | 0.79 | PNMT (0.46) | HTR7HTR1APNMTNPC1RAB9A | |
| SCHEMBL27639839 | 0.79 | PNMT (0.41) | HTR7HTR1APNMTNPC1RAB9A | |
| Fluorene SCHEMBL28444035 | 0.79 | PNMT (0.49) | HTR7HTR1APNMTNPC1RAB9A | |
| SCHEMBL6675750 | 0.77 | PNMT (0.50) | HTR7HTR1APNMTNPC1RAB9A | |
| SCHEMBL29555007 | 0.77 | PNMT (0.50) | HTR7HTR1APNMTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104003846-A | Indan-acetylaminofluorene and synthetic method thereof | UNIV SHANGHAI | 2014-08-27 | — | — | CN | disclosed |