Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 3/20 | 0.50 |
| ▸ | HCRTR2 | O43614 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | GHSR | Q92847 | 1/20 | 0.45 |
| ▸ | MMP1 | P03956 | 5/20 | 0.44 |
| ▸ | MMP3 | P08254 | 5/20 | 0.44 |
| ▸ | MMP7 | P09237 | 4/20 | 0.44 |
| ▸ | MMP13 | P45452 | 3/20 | 0.44 |
| ▸ | MMP2 | P08253 | 3/20 | 0.44 |
| ▸ | MMP9 | P14780 | 2/20 | 0.44 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.43 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.43 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.43 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.43 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.43 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.43 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27976150 | 1.00 | HCRTR1 (0.50) | HCRTR1HCRTR2LMNAHTTSMN1; SMN2 | |
| SCHEMBL27758830 | 0.96 | GHSR (0.50) | HCRTR1HCRTR2LMNAHTTGHSR | |
| SCHEMBL7981443 | 0.87 | MAPK1 (0.52) | LMNAHTTALDH1A1MAPT | |
| SCHEMBL28242970 | 0.85 | TRPA1 (0.61) | LMNASMN1; SMN2TRPA1ALDH1A1MAPT | |
| SCHEMBL28243001 | 0.85 | TRPA1 (0.61) | LMNASMN1; SMN2TRPA1ALDH1A1MAPT | |
| SCHEMBL28831491 | 0.82 | L3MBTL1 (0.51) | HCRTR1HCRTR2LMNASMN1; SMN2TRPA1 | |
| SCHEMBL6842733 | 0.82 | PSEN1 (0.50) | HTTMMP1MMP3MMP7MMP13 | |
| SCHEMBL18065224 | 0.80 | PSEN1 (0.66) | HCRTR1HCRTR2LMNAHTTSMN1; SMN2 | |
| SCHEMBL18065225 | 0.80 | PSEN1 (0.66) | HCRTR1HCRTR2LMNAHTTSMN1; SMN2 | |
| SCHEMBL3115162 | 0.79 | HCRTR1 (0.62) | HCRTR1HCRTR2SMN1; SMN2GHSRMMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104364246-A | Piperidine derivatives useful as GPR119 agonists | TOYOTA MOTOR CO LTD | 2015-02-18 | — | — | CN | disclosed |