Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 5/20 | 0.62 |
| ▸ | HCRTR2 | O43614 | 5/20 | 0.62 |
| ▸ | CASP3 | P42574 | 1/20 | 0.60 |
| ▸ | MMP1 | P03956 | 3/20 | 0.56 |
| ▸ | MMP3 | P08254 | 2/20 | 0.56 |
| ▸ | MMP7 | P09237 | 1/20 | 0.56 |
| ▸ | MMP13 | P45452 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | GHSR | Q92847 | 1/20 | 0.54 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.54 |
| ▸ | MMP2 | P08253 | 1/20 | 0.53 |
| ▸ | MMP9 | P14780 | 1/20 | 0.53 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3096773 | 1.00 | HCRTR1 (0.62) | HCRTR1HCRTR2CASP3MMP1MMP3 | |
| SCHEMBL5885922 | 0.88 | ALDH1A1 (0.70) | HCRTR1HCRTR2CASP3ALDH1A1KMT2A | |
| SCHEMBL5885924 | 0.88 | ALDH1A1 (0.70) | HCRTR1HCRTR2CASP3ALDH1A1KMT2A | |
| SCHEMBL21442025 | 0.86 | LMNA (0.62) | HCRTR1HCRTR2CASP3MMP1ALDH1A1 | |
| SCHEMBL16763213 | 0.86 | CASP3 (0.60) | HCRTR1HCRTR2CASP3MMP1MMP3 | |
| SCHEMBL16763211 | 0.86 | CASP3 (0.60) | HCRTR1HCRTR2CASP3MMP1MMP3 | |
| SCHEMBL7992848 | 0.86 | MMP1 (0.70) | HCRTR1HCRTR2MMP1MMP3MMP7 | |
| SCHEMBL3904609 | 0.86 | MMP2 (0.64) | CASP3ALDH1A1KMT2AFKBP1AMMP2 | |
| SCHEMBL695760 | 0.86 | MMP2 (0.64) | CASP3ALDH1A1KMT2AFKBP1AMMP2 | |
| SCHEMBL16014995 | 0.86 | CASP3 (0.62) | HCRTR1HCRTR2CASP3MMP1MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100016295-A1 | Preparation and Use of Biphenyl Amino Acid Derivatives for the Treatment of Obesity | BAYER HEALTHCARE LLC (US) | 2010-01-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100016295-A1 | Preparation and Use of Biphenyl Amino Acid Derivatives for the Treatment of Obesity | BCAT2, BCAT1, FABP4 | HCRTR1 912/4885HCRTR2 832/4885CASP3 1237/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.