2,4-Diaminophenol

2,4-Diaminophenol

SCHEMBL19327374

Nc1ccc(O)c(N)c1.Nc1ccc(OCCO)c(N)c1

nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.56
MAPT P10636 5/20 0.56
GAA P10253 4/20 0.56
KDM4E B2RXH2 3/20 0.56
MEN1 O00255 3/20 0.56
KMT2A Q03164 3/20 0.56
USP2 O75604 3/20 0.56
HTT P42858 2/20 0.56
TP53 P04637 2/20 0.56
POLB P06746 2/20 0.56
CASP1 P29466 1/20 0.56
CASP7 P55210 1/20 0.56
ATM Q13315 1/20 0.56
IDO1 P14902 1/20 0.47
PRSS1 P07477 8/20 0.42
PTGDR2 Q9Y5Y4 1/20 0.38
HSD17B10 Q99714 4/20 0.37
ALOX15 P16050 3/20 0.37
HPGD P15428 2/20 0.37
ALOX12 P18054 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL35916 0.91 MAPT (0.65) ALDH1A1MAPTGAAKDM4EMEN1
SCHEMBL29358757 0.91 MAPT (0.65) ALDH1A1MAPTGAAKDM4EMEN1
Hydrochloric Acid SCHEMBL1453993 0.90 GAA (0.68) ALDH1A1MAPTGAAKDM4EMEN1
Hydrochloric Acid SCHEMBL29378616 0.90 GAA (0.68) ALDH1A1MAPTGAAKDM4EMEN1
Ammonia Solution, Strong SCHEMBL27977263 0.90 MAPT (0.62) ALDH1A1MAPTGAAKDM4EMEN1
Hydrochloric Acid SCHEMBL29356501 0.90 GAA (0.68) ALDH1A1MAPTGAAKDM4EMEN1
Hydrochloric Acid SCHEMBL33976 0.90 GAA (0.68) ALDH1A1MAPTGAAKDM4EMEN1
SCHEMBL8091658 0.88 MAPT (0.61) ALDH1A1MAPTGAAKDM4EMEN1
Hydrochloric Acid SCHEMBL22612486 0.88 MAPT (0.61) ALDH1A1MAPTGAAKDM4EMEN1
Hydrochloric Acid SCHEMBL29148900 0.88 GAA (0.66) ALDH1A1MAPTGAAKDM4EMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11160737-B2 Keratin fiber dyeing composition BEAUTY & BUSINESS S.P.A. (IT) 2021-11-02 US disclosed
US-20210145718-A1 KERATIN FIBER DYEING COMPOSITION BEAUTY & BUSINESS S.P.A. (IT) 2021-05-20 US disclosed
US-20170290749-A1 KERATIN FIBRE BLEACHING COMPOSITION BEAUTY & BUSINESS S.P.A. (IT) 2017-10-12 US disclosed
US-20170258692-A1 KERATIN FIBRE DYEING COMPOSITION BEAUTY & BUSINESS S.P.A. (IT) 2017-09-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170258692-A1 KERATIN FIBRE DYEING COMPOSITION KRT18, CYB5R3, COL1A1 ALDH1A1 1214/4885MAPT 1070/4885GAA 4836/4885
US-20170290749-A1 KERATIN FIBRE BLEACHING COMPOSITION KRT18, KAT2B, CRYAB ALDH1A1 3530/4885MAPT 185/4885GAA 1020/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.