Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 3/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.32 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.32 |
| ▸ | BTK | Q06187 | 1/20 | 0.32 |
| ▸ | MRGPRX2 | Q96LB1 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17783841 | 0.69 | MEN1 (0.44) | — | |
| SCHEMBL28087528 | 0.69 | HTR2A (0.41) | MCHR1HTR2AHTR2C | |
| SCHEMBL16293345 | 0.68 | — | — | |
| SCHEMBL3574974 | 0.68 | MAPT (0.46) | MCHR1HRH3KDM4E | |
| SCHEMBL14970182 | 0.67 | SMN1; SMN2 (0.47) | — | |
| SCHEMBL3566234 | 0.67 | MCHR1 (0.60) | MCHR1 | |
| SCHEMBL16293975 | 0.66 | POLB (0.61) | — | |
| SCHEMBL26617983 | 0.65 | KDM4E (0.57) | MCHR1SLC6A2KDM4E | |
| SCHEMBL23603454 | 0.64 | SIGMAR1 (0.38) | MCHR1SLC6A2KDM4E | |
| SCHEMBL10202213 | 0.63 | NCF1 (0.46) | HTR2AHTR2CKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104011054-A | Thieno- and furo-pyrimidines and pyridines, useful as potassium channel inhibitors | XENTION LTD | 2014-08-27 | — | — | CN | disclosed |