Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.41 |
| ▸ | HTR2C | P28335 | 2/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 4/20 | 0.36 |
| ▸ | DRD4 | P21917 | 4/20 | 0.36 |
| ▸ | DRD3 | P35462 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ACACB | O00763 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3574974 | 0.82 | MAPT (0.46) | MCHR1SIGMAR1SMN1; SMN2MAPTGAA | |
| SCHEMBL3566234 | 0.78 | MCHR1 (0.60) | MCHR1SMN1; SMN2 | |
| SCHEMBL23603454 | 0.70 | SIGMAR1 (0.38) | MCHR1SIGMAR1 | |
| SCHEMBL24681691 | 0.69 | MCHR1 (0.54) | MCHR1MAPT | |
| SCHEMBL24681690 | 0.69 | MCHR1 (0.54) | MCHR1MAPT | |
| SCHEMBL10202213 | 0.69 | NCF1 (0.46) | HTR2AHTR2C | |
| SCHEMBL4560122 | 0.69 | ADRB1 (0.49) | HTR2AADRB1DRD2DRD4DRD3 | |
| SCHEMBL26762571 | 0.69 | SIGMAR1 (0.36) | MCHR1SIGMAR1 | |
| SCHEMBL27978705 | 0.69 | MCHR1 (0.41) | HTR2AHTR2CMCHR1 | |
| SCHEMBL2092625 | 0.68 | ADRB1 (0.59) | ADRB1SMN1; SMN2MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104011054-B | As the thieno of potassium channel inhibitors and Furanopyrimidines class and pyridines | 森申有限公司 | 2016-08-24 | — | — | CN | disclosed |