Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | QDPR | P09417 | 3/20 | 0.48 |
| ▸ | HTR6 | P50406 | 4/20 | 0.45 |
| ▸ | HTR2C | P28335 | 8/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.45 |
| ▸ | HTR7 | P34969 | 1/20 | 0.43 |
| ▸ | HTR1D | P28221 | 1/20 | 0.41 |
| ▸ | HTR1B | P28222 | 1/20 | 0.41 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.41 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.41 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.40 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.40 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16306719 | 0.76 | MMP13 (0.58) | FGFR1FGFR2FGFR3 | |
| SCHEMBL9974662 | 0.76 | HTR2C (0.59) | QDPRHTR6HTR2CSIGMAR1 | |
| SCHEMBL4283633 | 0.75 | HTR2C (0.52) | QDPRHTR6HTR2CSIGMAR1HTR7 | |
| SCHEMBL7859749 | 0.73 | HTR6 (0.45) | HTR6HTR2CSIGMAR1HTR7HTR1D | |
| SCHEMBL3956442 | 0.73 | QDPR (0.54) | QDPRHTR2CSIGMAR1HTR1DHTR1B | |
| SCHEMBL7955514 | 0.71 | QDPR (0.55) | QDPRHTR2CSIGMAR1 | |
| SCHEMBL5585398 | 0.70 | SIGMAR1 (0.65) | QDPRHTR6HTR2CSIGMAR1HTR7 | |
| SCHEMBL16142947 | 0.69 | HTR6 (0.42) | QDPRHTR6HTR2CSIGMAR1HTR7 | |
| SCHEMBL14956908 | 0.68 | QDPR (0.60) | QDPRHTR6HTR2CSIGMAR1HTR7 | |
| SCHEMBL6312184 | 0.68 | QDPR (0.55) | QDPRHTR6HTR2CSIGMAR1HTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104069112-A | Substituted piperidino-dihydrothienopyrimidines | BOEHRINGER INGELHEIM INT | 2014-10-01 | — | — | CN | disclosed |