Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 13/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7536673 | 0.84 | HSD11B1 (0.48) | HSD11B1EPHX1EPHX2FKBP1ACYP2C9 | |
| SCHEMBL333419 | 0.81 | HSD11B1 (0.46) | HSD11B1EPHX1EPHX2FKBP1ACYP2C9 | |
| SCHEMBL14112065 | 0.78 | ATM (0.57) | HSD11B1EPHX1EPHX2FKBP1ACYP2C9 | |
| SCHEMBL27533435 | 0.78 | ATM (0.57) | HSD11B1EPHX1EPHX2FKBP1ACYP2C9 | |
| SCHEMBL27869297 | 0.78 | HSD11B1 (0.43) | HSD11B1EPHX1EPHX2FKBP1ACYP2C9 | |
| SCHEMBL1337904 | 0.78 | HSD11B1 (0.43) | HSD11B1EPHX1EPHX2FKBP1ACYP2C9 | |
| SCHEMBL1033337 | 0.75 | HSD11B1 (0.52) | HSD11B1EPHX1EPHX2FKBP1ACYP2C9 | |
| SCHEMBL5350579 | 0.75 | HSD11B1 (0.52) | HSD11B1EPHX1EPHX2FKBP1ACYP2C9 | |
| SCHEMBL9101852 | 0.74 | HSD11B1 (0.40) | HSD11B1EPHX1EPHX2FKBP1ACYP2C9 | |
| SCHEMBL7538699 | 0.74 | HCAR2 (0.48) | HSD11B1EPHX1EPHX2FKBP1ACYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104496799-A | Preparation method of 2-(3-hydroxyl-1-adamantyl)-2-formylformic acid | LIANYUNGANG TECHNICAL COLLEGE | 2015-04-08 | — | — | CN | disclosed |