Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 9/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | EDNRA | P25101 | 5/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | EDNRB | P24530 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1337904 | 0.87 | HSD11B1 (0.43) | HSD11B1EPHX1ATMFKBP1AEPHX2 | |
| SCHEMBL27869297 | 0.87 | HSD11B1 (0.43) | HSD11B1EPHX1ATMFKBP1AEPHX2 | |
| SCHEMBL7536673 | 0.83 | HSD11B1 (0.48) | HSD11B1EPHX1ATMFKBP1AEPHX2 | |
| SCHEMBL27533435 | 0.77 | ATM (0.57) | HSD11B1EPHX1ATMFKBP1AEPHX2 | |
| SCHEMBL14112065 | 0.77 | ATM (0.57) | HSD11B1EPHX1ATMFKBP1AEPHX2 | |
| SCHEMBL7538699 | 0.76 | HCAR2 (0.48) | HSD11B1EPHX1ATMFKBP1AEPHX2 | |
| SCHEMBL27985247 | 0.74 | HSD11B1 (0.47) | HSD11B1EPHX1ATMFKBP1AEPHX2 | |
| SCHEMBL333419 | 0.72 | HSD11B1 (0.46) | HSD11B1EPHX1ATMFKBP1AEPHX2 | |
| SCHEMBL20768339 | 0.71 | HSD11B1 (0.44) | HSD11B1EPHX1FKBP1AEPHX2CYP2C9 | |
| SCHEMBL8395211 | 0.70 | HSD11B1 (0.47) | HSD11B1EPHX1FKBP1AEPHX2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10889146-B2 | Tire object provided with an elastomer layer made of a thermoplastic elastomer in the form of an (A-b-(a-methylstyrene-co-B))n-b-C block copolymer | COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) | 2021-01-12 | — | — | US | disclosed |
| CN-104812790-B | Organopolysiloxane graft polymers | 花王株式会社 | 2019-04-12 | — | — | CN | disclosed |
| EP-2927253-B1 | ORGANOPOLYSILOXANE GRAFT POLYMER | KAO CORP (JP) | 2018-09-12 | — | — | EP | disclosed |
| US-10030131-B2 | Pneumatic object provided with a gastight layer containing a thermoplastic elastomer and a thermoplastic | COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) | 2018-07-24 | — | — | US | disclosed |
| US-9914328-B2 | Inflatable object provided with a gas-tight layer containing a thermoplastic elastomer and a hydrocarbon-based resin | COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (CH) | 2018-03-13 | — | — | US | disclosed |
| US-20180043734-A1 | TIRE OBJECT PROVIDED WITH AN ELASTOMER LAYER MADE OF A THERMOPLASTIC ELASTOMER IN THE FORM OF AN (A-B-(A-METHYLSTYRENE-CO-B))N-B-C BLOCK COPOLYMER | COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) | 2018-02-15 | — | — | US | disclosed |
| US-9351920-B2 | Organopolysiloxane graft polymer | KAO CORPORATION (JP) | 2016-05-31 | — | — | US | disclosed |
| US-20150297498-A1 | ORGANOPOLYSILOXANE GRAFT POLYMER | KAO CORPORATION (JP) | 2015-10-22 | — | — | US | disclosed |
| US-20150290975-A1 | PNEUMATIC TIRE WITH AN INNER LINER BONDED BY A FIBRE ASSEMBLY | COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) | 2015-10-15 | — | — | US | disclosed |
| EP-2927253-A1 | ORGANOPOLYSILOXANE GRAFT POLYMER | Kao Corporation (JP) | 2015-10-07 | — | — | EP | disclosed |
| US-20140343216-A1 | TIRE PROVIDED WITH AN INNER LAYER COMPRISING A MIXTURE OF A DIENE ELASTOMER AND A THERMOPLASTIC ELASTOMER | MICHELIN RECHERCHE ET TECHNIQUE S.A. (CH) | 2014-11-20 | — | — | US | disclosed |
| US-20140343190-A1 | TIRE PROVIDED WITH A TREAD MADE FROM A MIXTURE OF A DIENE ELASTOMER AND A THERMOPLASTIC ELASTOMER | MICHELIN RECHERCHE ET TECHNIQUE S.A. (CH) | 2014-11-20 | — | — | US | disclosed |
| US-20140299249-A1 | TIRE PROVIDED WITH AN OUTER SIDEWALL COMPRISING A MIXTURE OF A DIENE ELASTOMER AND A THERMOPLASTIC ELASTOMER | MICHELIN RECHERCHE ET TECHNIQUE S.A. (CH) | 2014-10-09 | — | — | US | disclosed |
| US-20130209716-A1 | INFLATABLE ARTICLE PROVIDED WITH GAS-IMPERMEABLE LAYER BASED ON A BLEND OF A BUTYL RUBBER AND A THERMOPLASTIC ELASTOMER | MICHELIN RECHERCHE ET TECHNIQUE S.A. (CH) | 2013-08-15 | — | — | US | disclosed |
| US-20130196086-A1 | INFLATABLE OBJECT PROVIDED WITH A GAS-TIGHT LAYER CONTAINING A THERMOPLASTIC ELASTOMER AND A HYDROCARBON-BASED RESIN | MICHELIN RECHERCHE ET TECHNIQUE S.A. (CH) | 2013-08-01 | — | — | US | disclosed |
| US-20130168001-A1 | PNEUMATIC OBJECT PROVIDED WITH A GAS-TIGHT LAYER COMPRISING A MIXTURE OF A THERMOPLASTIC ELASTOMER AND A BUTYL RUBBER | MICHELIN RECHERCHE ET TECHNIQUE S.A. (CH) | 2013-07-04 | — | — | US | disclosed |
| US-20130072621-A1 | PNEUMATIC OBJECT PROVIDED WITH A GASTIGHT LAYER CONTAINING A THERMOPLASTIC ELASTOMER AND A THERMOPLASTIC | MICHELIN RECHERCHE ET TECHNIQUE S.A. (CH) | 2013-03-21 | — | — | US | disclosed |
| US-20120315408-A1 | INFLATABLE ARTICLE PROVIDED WITH A GASTIGHT LAYER BASED ON A BLEND OF A THERMOPLASTIC ELASTOMER AND OF A PARTIALLY CROSSLINKED BUTYL RUBBER. | MICHELIN RECHERCHE ET TECHNIQUE S.A. (CH) | 2012-12-13 | — | — | US | disclosed |
| US-20120149822-A1 | PNEUMATIC OBJECT PROVIDED WITH A GASTIGHT LAYER MADE OF A THERMOPLASTIC ELASTOMER AND LAMELLAR FILLER | MICHELIN RECHERCHE ET TECHNIQUE S.A. (CH) | 2012-06-14 | — | — | US | disclosed |
| US-20120141696-A1 | ELASTOMER COMPOSITION MADE FROM A THERMOPLASTIC COPOLYMER, INFLATABLE OBJECT PROVIDED WITH A GAS BARRIER MADE FROM SUCH A COMPOSITION | SOCIETE DE TECHNOLOGIE MICHELIN (FR) | 2012-06-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150297498-A1 | ORGANOPOLYSILOXANE GRAFT POLYMER | IDUA, PIGS, GMNN | HSD11B1 3687/4885EPHX1 1263/4885EDNRA 3741/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.