SCHEMBL7538699

SCHEMBL7538699

CC(C)OC(=O)C=CC(=O)OC1C2CC3CC(C2)CC1C3

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 1/20 0.48
HSD11B1 P28845 5/20 0.43
ATM Q13315 1/20 0.38
EPHX1 P07099 1/20 0.38
EPHX2 P34913 4/20 0.38
CA12 O43570 1/20 0.36
AKR1B10 O60218 1/20 0.36
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
AKR1B1 P15121 1/20 0.36
CA7 P43166 1/20 0.36
CA9 Q16790 1/20 0.36
CA14 Q9ULX7 1/20 0.36
FKBP1A P62942 1/20 0.33
CYP2C9 P11712 1/20 0.32
CTSV O60911 1/20 0.31
CTSL P07711 1/20 0.31
CTSS P25774 1/20 0.31
CTSK P43235 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7536673 0.87 HSD11B1 (0.48) HSD11B1ATMEPHX1EPHX2FKBP1A
SCHEMBL1337904 0.80 HSD11B1 (0.43) HSD11B1ATMEPHX1EPHX2FKBP1A
SCHEMBL14112065 0.80 ATM (0.57) HCAR2HSD11B1ATMEPHX1EPHX2
SCHEMBL27533435 0.80 ATM (0.57) HCAR2HSD11B1ATMEPHX1EPHX2
SCHEMBL27869297 0.80 HSD11B1 (0.43) HSD11B1ATMEPHX1EPHX2FKBP1A
SCHEMBL9101852 0.76 HSD11B1 (0.40) HSD11B1ATMEPHX1EPHX2FKBP1A
SCHEMBL177747 0.74 HCAR2 (0.80) HCAR2ATMCA12AKR1B10CA1
SCHEMBL178194 0.74 HCAR2 (0.80) HCAR2ATMCA12AKR1B10CA1
SCHEMBL177748 0.74 HCAR2 (0.80) HCAR2ATMCA12AKR1B10CA1
SCHEMBL27985247 0.74 HSD11B1 (0.47) HSD11B1ATMEPHX1EPHX2FKBP1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020190818-A1 High frequency band pass filter TDK CORPORATION (JP) 2002-12-19 US disclosed
EP-0788118-B1 Low dielectric polymer and film, substrate and electronic part using the same TDK CORP (JP) 2002-11-20 EP disclosed
US-5914283-A FUMARIC ACID DIESTER MONOMER-CONTAINING POLYMER FILM; HEAT RESISTANCE, WEATHER RESISTANCE TDK CORPORATION (JP) 1999-06-22 US disclosed
EP-0788118-A1 Low dielectric polymer and film, substrate and electronic part using the same TDK Corporation (JP) 1997-08-06 EP disclosed