Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.57 |
| ▸ | HSD11B1 | P28845 | 5/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | HCAR2 | Q8TDS4 | 5/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.35 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.35 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14112065 | 1.00 | ATM (0.57) | ATMHSD11B1THRBCYP2C9EPHX1 | |
| SCHEMBL7536673 | 0.92 | HSD11B1 (0.48) | ATMHSD11B1THRBCYP2C9EPHX1 | |
| SCHEMBL1337904 | 0.81 | HSD11B1 (0.43) | ATMHSD11B1CYP2C9EPHX1EPHX2 | |
| SCHEMBL27869297 | 0.81 | HSD11B1 (0.43) | ATMHSD11B1CYP2C9EPHX1EPHX2 | |
| SCHEMBL7538699 | 0.80 | HCAR2 (0.48) | ATMHSD11B1CYP2C9EPHX1HCAR2 | |
| SCHEMBL27985247 | 0.78 | HSD11B1 (0.47) | ATMHSD11B1CYP2C9EPHX1EPHX2 | |
| SCHEMBL4953819 | 0.78 | HCAR2 (0.46) | ATMHSD11B1THRBCYP2C9EPHX1 | |
| SCHEMBL9101852 | 0.77 | HSD11B1 (0.40) | ATMHSD11B1CYP2C9EPHX1EPHX2 | |
| SCHEMBL333419 | 0.76 | HSD11B1 (0.46) | ATMHSD11B1CYP2C9EPHX1EPHX2 | |
| Adamantane SCHEMBL2307508 | 0.76 | THRB (0.61) | ATMHSD11B1THRBCYP2C9HCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1255505-A | Fumarate diester resin compsns. and its cross-linked diester fumarate resin | NIPPON OILS & FATS CO LTD (JP) | 2000-06-07 | — | — | CN | disclosed |