SCHEMBL2625726

SCHEMBL2625726

O=Cc1cccc(Br)c1[N+](=O)[O-]

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ERN1 O75460 4/20 0.49
ALDH1A1 P00352 4/20 0.41
TDP1 Q9NUW8 3/20 0.41
CYP2A6 P11509 1/20 0.40
LMNA P02545 3/20 0.39
MEN1 O00255 1/20 0.39
THRB P10828 1/20 0.39
BLM P54132 1/20 0.39
KMT2A Q03164 1/20 0.39
MAPT P10636 2/20 0.39
HSP90AA1 P07900 1/20 0.39
ATM Q13315 1/20 0.39
PMM2 O15305 1/20 0.38
MPI P34949 1/20 0.38
TRIM24 O15164 1/20 0.37
TRIM33 Q9UPN9 1/20 0.37
TSHR P16473 2/20 0.36
GPR35 Q9HC97 1/20 0.36
POLB P06746 1/20 0.34
PIM1 P11309 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9417632 0.86 ERN1 (0.57) ERN1ALDH1A1TDP1LMNAMEN1
SCHEMBL16958093 0.83 ALDH1A1 (0.41) ERN1ALDH1A1TDP1LMNAMEN1
SCHEMBL2402265 0.83 ALDH1A1 (0.41) ERN1ALDH1A1TDP1LMNAMEN1
SCHEMBL9452627 0.81 ALDH1A1 (0.52) ALDH1A1TDP1LMNAPMM2MPI
SCHEMBL31448604 0.81 LMNA (0.46) ERN1ALDH1A1TDP1LMNAMEN1
SCHEMBL196088 0.78 ERN1 (0.65) ERN1ALDH1A1TDP1LMNAMEN1
SCHEMBL2841960 0.78 ERN1 (0.50) ERN1ALDH1A1TDP1LMNAMEN1
SCHEMBL27935920 0.78 ERN1 (0.65) ERN1ALDH1A1TDP1LMNAMEN1
SCHEMBL27985682 0.78 ERN1 (0.50) ERN1ALDH1A1TDP1LMNAMEN1
SCHEMBL722136 0.77 ALDH1A1 (0.67) ERN1ALDH1A1TDP1LMNAMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 110 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103880683-B A kind of chemical synthesis process of the bromo- 2- nitrobenzaldehydes of 3- 南通大学 2018-06-22 CN claimed
CN-105419785-B Multi-photon polarization laser material being combined based on metal organic frame host and guest build and preparation method thereof 浙江大学 2017-06-16 CN claimed
CN-105669566-A Preparation method of pharmaceutical intermediate N-arylquinazolinyl-amine compounds 华东师范大学 2016-06-15 CN claimed
CN-105419785-A Subject and object compounded multi-photon polarization laser material based on metal-organic framework and preparation method of subject and object compounded multi-photon polarization laser material UNIV ZHEJIANG 2016-03-23 CN claimed
CN-103880683-A Chemical synthesis method of 3-bromo-2-nitrobenzaldehyde UNIV NANTONG 2014-06-25 CN claimed
WO-2026103853-A1 TSHR ANTAGONIST COMPOUND, PHARMACEUTICAL COMPOSITION, METHOD FOR PREPARING SAME, AND USE THEREOF 长春金赛药业有限责任公司 2026-05-21 WO disclosed
US-20260107676-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2026-04-16 US disclosed
US-20250361210-A1 3,4-DIHYDROQUINOLIN-2(1H)-ONE COMPOUND KISSEI PHARMACEUTICAL CO., LTD. (JP) 2025-11-27 US disclosed
US-12281065-B2 Iron catalyzed highly enantioselective cis-dihydroxylation of quinones VERSITECH LIMITED (CN) 2025-04-22 US disclosed
CN-114269720-B Acetyl-coa synthetase short chain2(ACSS2) Small molecule inhibitors of (a) 库拉德夫制药私人有限公司 2025-03-28 CN disclosed
EP-4512801-A1 3,4-DIHYDROQUINOLIN-2(1H)-ONE COMPOUND Kissei Pharmaceutical Co., Ltd. (JP) 2025-02-26 EP disclosed
CN-119343332-A 3, 4-Dihydro-quinolin-2 (1H) -one compounds 橘生药品工业株式会社 2025-01-21 CN disclosed
US-20080051384-A1 ANTIVIRAL AGENTS GENELABS TECHNOLOGIES, INC. 2008-02-28 US disclosed
WO-2008008912-A1 ANTIVIRAL AGENTS GENELABS TECHNOLOGIES, INC. (US) 2008-01-17 WO disclosed
WO-2008008907-A2 ANTIVIRAL AGENTS GENELABS TECHNOLOGIES, INC. (US) 2008-01-17 WO disclosed
CN-101103026-A Bicyclic heteroaryl derivatives for treating viruses GENELABS INC (US) 2008-01-09 CN disclosed
EP-1844042-A1 INDOLE DERIVATIVES FOR TREATING VIRAL INFECTIONS GENELABS TECHNOLOGIES, INC. (US) 2007-10-17 EP disclosed
WO-2007109334-A2 SIP RECEPTOR MODULATING COMPOUNDS AND USE THEREOF EPIX DELAWARE, INC. (US) 2007-09-27 WO disclosed
US-20060211698-A1 Bicyclic heteroaryl derivatives for treating viruses GENELABS, INC. 2006-09-21 US disclosed
WO-2006076529-A1 INDOLE DERIVATIVES FOR TREATING VIRAL INFECTIONS GENELABS TECHNOLOGIES, INC. (US) 2006-07-20 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260107676-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES LBR, GLRB, OPRD1 ERN1 803/4885ALDH1A1 1871/4885TDP1 4675/4885
US-12281065-B2 Iron catalyzed highly enantioselective cis-dihydroxylation of quinones NFE2L2, DUOX1, DUOX2 ERN1 3677/4885ALDH1A1 323/4885TDP1 3920/4885
US-20060211698-A1 Bicyclic heteroaryl derivatives for treating viruses HAVCR2, ZC3HAV1, SARS1 ERN1 653/4885ALDH1A1 1627/4885TDP1 2016/4885
US-20080051384-A1 ANTIVIRAL AGENTS EIF2AK2, MAVS, ZC3HAV1 ERN1 132/4885ALDH1A1 1357/4885TDP1 1009/4885
US-20250361210-A1 3,4-DIHYDROQUINOLIN-2(1H)-ONE COMPOUND TSHR, TRHR, GHSR ERN1 3831/4885ALDH1A1 1515/4885TDP1 2580/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.