Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.47 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | GRM5 | P41594 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | PMM2 | O15305 | 1/20 | 0.43 |
| ▸ | MPI | P34949 | 1/20 | 0.43 |
| ▸ | PHOSPHO1 | Q8TCT1 | 1/20 | 0.43 |
| ▸ | KDM6B | O15054 | 1/20 | 0.43 |
| ▸ | KDM5C | P41229 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10783183 | 0.83 | TP53 (0.51) | TP53ADORA2AADORA1ALDH1A1HPGD | |
| SCHEMBL15577161 | 0.82 | ADORA2A (0.56) | ADORA2AADORA1ALDH1A1HPGDMAPT | |
| SCHEMBL15578745 | 0.79 | RPA1 (0.53) | ADORA2AALDH1A1RAB9A | |
| SCHEMBL32674134 | 0.79 | MAPT (0.59) | ADORA2AADORA1ALDH1A1HPGDMAPT | |
| SCHEMBL10783819 | 0.79 | TP53 (0.47) | TP53ADORA2AADORA1ALDH1A1HPGD | |
| SCHEMBL15577228 | 0.77 | PKM (0.56) | ALDH1A1MAPTL3MBTL1KDM4EGAA | |
| SCHEMBL1752087 | 0.76 | P2RX7 (0.53) | ALDH1A1HPGDKDM4ERAB9ATSHR | |
| SCHEMBL27988017 | 0.76 | GRM5 (0.56) | TP53ALDH1A1HPGDCYP1A2CYP2D6 | |
| SCHEMBL15577160 | 0.76 | ADAMTS7 (0.49) | MAPTKDM4EMAPK1RAB9A | |
| SCHEMBL6165168 | 0.75 | HPGDS (0.61) | TP53ALDH1A1HPGDCYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104159892-A | Substituted phenyl azole derivatives | DAIICHI SANKYO CO LTD | 2014-11-19 | — | — | CN | disclosed |