SCHEMBL27987679

SCHEMBL27987679

CC(C)(C)c1ccc(C2=CC=C[CH]2)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 4/20 0.43
TSHR P16473 1/20 0.41
LMNA P02545 2/20 0.39
TYR P14679 1/20 0.39
NPC1 O15118 5/20 0.38
RAB9A P51151 5/20 0.38
ALDH1A1 P00352 4/20 0.37
KDM4E B2RXH2 3/20 0.37
KMT2A Q03164 2/20 0.37
HTR1D P28221 1/20 0.35
ADRA1A P35348 1/20 0.35
NISCH Q9Y2I1 1/20 0.35
XDH P47989 1/20 0.35
CYP1A2 P05177 1/20 0.34
TP53 P04637 2/20 0.34
SMN1; SMN2 Q16637 2/20 0.34
MITF O75030 1/20 0.34
DGAT1 O75907 1/20 0.33
HTT P42858 1/20 0.33
NOTUM Q6P988 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28814852 0.78 GABRA1 (0.39) KDM4E
SCHEMBL28185415 0.75 ACHE (0.40) KIF11NPC1RAB9AALDH1A1KDM4E
SCHEMBL3423876 0.72 KIF11 (0.70) KIF11TSHRLMNATYRNPC1
SCHEMBL26915 0.72 KIF11 (0.70) KIF11TSHRLMNATYRNPC1
SCHEMBL5264518 0.72 KIF11 (0.39) KIF11TSHRLMNATYRNPC1
SCHEMBL28779361 0.71 TSHR (0.43) KIF11TSHRLMNATYRNPC1
Lithium SCHEMBL29536927 0.70 KIF11 (0.67) KIF11TSHRLMNATYRNPC1
Lithium SCHEMBL30081449 0.70 KIF11 (0.67) KIF11TSHRLMNATYRNPC1
SCHEMBL1931781 0.70 KIF11 (0.67) KIF11TSHRLMNATYRNPC1
SCHEMBL27987749 0.70 CYP1A2 (0.40) TSHRLMNANPC1RAB9AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104203996-B Multimodal polyolefin resin and formed body prepared therefrom 大林产业株式会社 2018-04-20 CN disclosed
CN-104203996-A Multimodal polyolefin resin and molded product prepared therefrom DAELIM IND CO LTD 2014-12-10 CN disclosed