SCHEMBL28814852

SCHEMBL28814852

CC(C)(C)c1cc(C2=CC=C[CH]2)cc(C(C)(C)C)c1

nearest known ligand 0.39

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 1/20 0.39
GABRB2 P47870 1/20 0.39
KDM4E B2RXH2 1/20 0.38
GAA P10253 1/20 0.38
MAPT P10636 1/20 0.38
RXRB P28702 6/20 0.37
RXRA P19793 5/20 0.37
RXRG P48443 3/20 0.36
POLB P06746 1/20 0.32
S1PR1 P21453 1/20 0.31
S1PR3 Q99500 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27987679 0.78 KIF11 (0.43) KDM4E
SCHEMBL4572745 0.72 GABRA1 (0.58) GABRA1GABRB2KDM4EGAAMAPT
SCHEMBL26230931 0.70 GABRA1 (0.55) GABRA1GABRB2KDM4EGAAMAPT
SCHEMBL27987688 0.70 ALDH1A1 (0.33) RXRBRXRA
SCHEMBL93161 0.69 GABRA1 (0.69) GABRA1GABRB2KDM4EGAAMAPT
SCHEMBL10415675 0.66 GABRA1 (0.65) GABRA1GABRB2KDM4EGAAMAPT
SCHEMBL10394690 0.66 GABRA1 (0.65) GABRA1GABRB2KDM4EGAAMAPT
SCHEMBL4526927 0.66 RXRB (0.65) GABRA1GABRB2KDM4EGAAMAPT
SCHEMBL414084 0.66 RXRB (0.65) GABRA1GABRB2KDM4EGAAMAPT
SCHEMBL27987681 0.65 ALDH1A1 (0.48) GAAMAPTRXRA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104203996-B Multimodal polyolefin resin and formed body prepared therefrom 大林产业株式会社 2018-04-20 CN disclosed
CN-104203996-A Multimodal polyolefin resin and molded product prepared therefrom DAELIM IND CO LTD 2014-12-10 CN disclosed