Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 2/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 6/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 6/20 | 0.31 |
| ▸ | DAO | P14920 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 2/20 | 0.30 |
| ▸ | RAB9A | P51151 | 2/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.30 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
| ▸ | CASP3 | P42574 | 1/20 | 0.30 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.30 |
| ▸ | RELA | Q04206 | 1/20 | 0.30 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.30 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.30 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | RXRA | P19793 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16434936 | 0.78 | GRIN1 (0.37) | MCHR1GRIN1GRIN2BNPC1RAB9A | |
| SCHEMBL16434686 | 0.78 | ROCK2 (0.36) | GRIN1GRIN2BNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL16434807 | 0.78 | ALDH1A1 (0.37) | ALDH1A1 | |
| SCHEMBL27989031 | 0.78 | EGLN2 (0.35) | — | |
| SCHEMBL27989219 | 0.75 | LIPG (0.33) | ENPP2 | |
| SCHEMBL27988983 | 0.72 | GRIN1 (0.38) | GRIN1GRIN2B | |
| SCHEMBL18033564 | 0.71 | DDR1 (0.33) | MCHR1GRIN1GRIN2BNPC1RAB9A | |
| SCHEMBL27989226 | 0.71 | ADRB1 (0.43) | ALDH1A1 | |
| SCHEMBL16534496 | 0.69 | GAA (0.40) | NPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL27988982 | 0.68 | CACNA1G (0.38) | SMN1; SMN2ENPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104203928-A | Triazinone compound and T-type calcium channel inhibitor | NISSAN CHEMICAL IND LTD | 2014-12-10 | — | — | CN | disclosed |