Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 3/20 | 0.55 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.55 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.49 |
| ▸ | KAT6A | Q92794 | 2/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.42 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.41 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.40 |
| ▸ | MAP1LC3A | Q9H492 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27953652 | 0.88 | LOXL2 (0.53) | CYP4F2CYP4A11LOXL2KAT6ASLC7A5 | |
| SCHEMBL28398121 | 0.86 | CYP4F2 (0.58) | CYP4F2CYP4A11LOXL2KAT6AALOX5 | |
| SCHEMBL1696378 | 0.85 | CYP4F2 (0.76) | CYP4F2CYP4A11LOXL2KAT6ASLC7A5 | |
| SCHEMBL27986137 | 0.83 | CYP4F2 (0.55) | CYP4F2CYP4A11LOXL2KAT6AALOX5 | |
| SCHEMBL12035616 | 0.83 | CYP4F2 (0.75) | CYP4F2CYP4A11MEP1BMAPTSMN1; SMN2 | |
| SCHEMBL15344632 | 0.82 | LMNA (0.62) | CYP4F2CYP4A11LOXL2SLC7A5MAPT | |
| SCHEMBL5382573 | 0.81 | SLC7A5 (0.60) | CYP4F2CYP4A11LOXL2KAT6AALOX5 | |
| SCHEMBL11752450 | 0.80 | KAT6A (0.52) | CYP4F2CYP4A11LOXL2KAT6AALOX5 | |
| SCHEMBL15344564 | 0.80 | CYP4F2 (0.61) | CYP4F2CYP4A11SMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL991080 | 0.79 | FOLH1 (0.61) | KAT6AMRGPRX4TP53PKMNFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102351791-B | Cyanoisoquinoline compounds capable of making hypoxia inducible factor (HIF) stable | FIBROGEN INC. (US) | 2014-10-29 | — | — | CN | disclosed |