Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KIF11 | P52732 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | FABP3 | P05413 | 1/20 | 0.33 |
| ▸ | FABP4 | P15090 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27992361 | 0.83 | ALDH1A1 (0.36) | ALDH1A1GAAALOX12CYP2C19RAB9A | |
| SCHEMBL27992415 | 0.83 | HDAC6 (0.38) | ALDH1A1GAAALOX12CYP2C19NPC1 | |
| SCHEMBL1014939 | 0.75 | KCNN4 (0.40) | HTTHTR2AHTR2CADRA1AOPRK1 | |
| SCHEMBL27992131 | 0.74 | TAS1R3 (0.38) | HTTALDH1A1HPGDNPC1RAB9A | |
| SCHEMBL27993000 | 0.72 | HTR2A (0.40) | HTTHTR2AHTR2CADRA1AOPRK1 | |
| SCHEMBL5027223 | 0.71 | PDK1 (0.41) | HTTHTR2AHTR2CADRA1AOPRK1 | |
| SCHEMBL3447426 | 0.69 | PDE2A (0.43) | HTTHTR2AHTR2CADRA1AOPRK1 | |
| SCHEMBL16055331 | 0.69 | LMNA (0.37) | HTTADRA1AOPRK1ALDH1A1HPGD | |
| SCHEMBL27992199 | 0.68 | ADRB2 (0.33) | HTTHTR2AHTR2CADRA1AOPRK1 | |
| SCHEMBL27992241 | 0.68 | ADRB2 (0.33) | HTTHTR2AHTR2CADRA1AOPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104136416-B | Phenylalkylamino carbamate derivatives compound and comprise the pharmaceutical composition of this Phenylalkylamino carbamate derivatives compound | 比皮艾思药物研发有限公司 | 2016-11-09 | — | — | CN | disclosed |
| CN-105209027-A | Phenylalkylcarbamate compounds for use in the prevention or treatment of epilepsy and epilepsy-related syndromes | BIO PHARM SOLUTIONS CO LTD | 2015-12-30 | — | — | CN | disclosed |
| CN-104136416-A | Phenyl alkyl carbamate derivative compound and pharmaceutical composition containing the same | BIO PHARM SOLUTIONS CO LTD | 2014-11-05 | — | — | CN | disclosed |