SCHEMBL28001986

SCHEMBL28001986

NC(C(=O)c1cccc(O)c1O)c1ccccc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 7/20 0.42
ALDH1A1 P00352 7/20 0.42
HPGD P15428 7/20 0.42
CA1 P00915 2/20 0.42
CA2 P00918 2/20 0.42
CA6 P23280 2/20 0.42
CA12 O43570 1/20 0.42
HMGB1 P09429 1/20 0.42
CA4 P22748 1/20 0.42
CA7 P43166 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
CA9 Q16790 1/20 0.42
NAPRT Q6XQN6 1/20 0.42
CA14 Q9ULX7 1/20 0.42
HSD17B10 Q99714 6/20 0.42
LMNA P02545 3/20 0.42
TSHR P16473 2/20 0.42
G6PD P11413 1/20 0.42
CASP7 P55210 1/20 0.42
CASP6 P55212 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7618886 0.88 TERT (0.45) KDM4EALDH1A1HPGDCA1CA2
SCHEMBL621111 0.81 LMNA (0.53) KDM4EALDH1A1HPGDCA1CA2
SCHEMBL16028845 0.81 SRC (0.55) KDM4EALDH1A1HPGDCA1CA2
SCHEMBL4879758 0.77 TERT (0.43) KDM4EALDH1A1HPGDCA1CA2
Methoxymethane SCHEMBL28820467 0.76 LMNA (0.47) KDM4EALDH1A1HPGDCA1CA2
SCHEMBL6069780 0.75 KDM4E (0.49) KDM4EALDH1A1HPGDCA1CA2
SCHEMBL15981547 0.72 TERT (0.46) KDM4EALDH1A1HPGDCA1CA2
SCHEMBL4919231 0.71 TDP1 (0.61) ALDH1A1SMN1; SMN2NAPRTHSD17B10LMNA
2,3-Dihydroxybenzoic Acid SCHEMBL10534711 0.71 ALDH1A1 (0.67) KDM4EALDH1A1HPGDCA1CA2
SCHEMBL3658372 0.71 TDP1 (0.61) ALDH1A1SMN1; SMN2NAPRTHSD17B10LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110066782-B Recombinant furin substantially free of animal proteins and method for producing same 武田药品工业株式会社 2024-04-16 CN disclosed
CN-109370980-B High-yield transient expression system 生命技术公司 2023-05-09 CN disclosed
CN-110066782-A The substantially recombinant furin and its production method of animal protein-free 百深有限责任公司 2019-07-30 CN disclosed
CN-109370980-A High yield transient expression system 生命技术公司 2019-02-22 CN disclosed
CN-104364369-B High yield transient expression in mammalian cells using unique pairs of high density growth and transfection media and expression enhancers 生命技术公司 2018-09-07 CN disclosed
CN-107922961-A Systems and methods for improved transient protein expression in CHO cells 生命技术公司 2018-04-17 CN disclosed
CN-104364369-A High yield transient expression in mammalian cells using unique pairs of high density growth and transfection media and expression enhancers LIFE TECHNOLOGIES CORP 2015-02-18 CN disclosed