Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | PRNP | P04156 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.32 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.32 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.31 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | METAP2 | P50579 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | CASP3 | P42574 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27817087 | 0.75 | P2RX7 (0.30) | — | |
| SCHEMBL28002690 | 0.66 | LMNA (0.34) | — | |
| SCHEMBL28003002 | 0.66 | CYP1A2 (0.30) | ALDH1A1KDM4E | |
| SCHEMBL28003039 | 0.65 | KDM4E (0.36) | ALDH1A1KDM4EGAAIDO1 | |
| SCHEMBL28002712 | 0.65 | TAAR1 (0.35) | RXFP1IDO1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL28003061 | 0.65 | CYP2A6 (0.42) | ALDH1A1KDM4EMETAP2SMN1; SMN2NISCH | |
| SCHEMBL28714551 | 0.63 | GAA (0.37) | DCUN1D1ALDH1A1PBRM1TNKS2GAA | |
| SCHEMBL25721326 | 0.61 | TSHR (0.43) | DCUN1D1ALDH1A1PKMKDM4EGAA | |
| SCHEMBL197690 | 0.61 | ACHE (0.64) | DCUN1D1ALDH1A1GAAIDO1METAP2 | |
| SCHEMBL30354037 | 0.61 | ACHE (0.64) | DCUN1D1ALDH1A1GAAIDO1METAP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104411709-B | Can be used as imidazo [2, the 1] thiazole-3-ketone derivatives of the diagnostic agent of Alzheimer | 霍夫曼-拉罗奇有限公司 | 2016-08-24 | — | — | CN | disclosed |
| CN-104411709-A | Imidazo [2,1]thiazol-3-one derivatives useful as diagnostic agents for alzheimer's disease | HOFFMANN LA ROCHE | 2015-03-11 | — | — | CN | disclosed |