Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 2/20 | 0.34 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.32 |
| ▸ | RELA | Q04206 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.32 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.31 |
| ▸ | HTR7 | P34969 | 1/20 | 0.31 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.31 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28003039 | 0.81 | KDM4E (0.36) | TAAR1IDO1PGRNOTUM | |
| SCHEMBL28079677 | 0.81 | KDM1A (0.40) | IDO1NOTUM | |
| SCHEMBL27817087 | 0.80 | P2RX7 (0.30) | — | |
| SCHEMBL28002692 | 0.77 | XDH (0.38) | — | |
| SCHEMBL28003061 | 0.72 | CYP2A6 (0.42) | NISCHSMN1; SMN2 | |
| SCHEMBL28002690 | 0.70 | LMNA (0.34) | NOTUM | |
| SCHEMBL28003002 | 0.70 | CYP1A2 (0.30) | — | |
| SCHEMBL28831583 | 0.70 | NISCH (0.32) | NISCH | |
| SCHEMBL28002684 | 0.65 | DCUN1D1 (0.33) | IDO1NISCHNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL198702 | 0.64 | TAAR1 (0.68) | TAAR1ESR2IDO1NISCHNOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104411709-B | Can be used as imidazo [2, the 1] thiazole-3-ketone derivatives of the diagnostic agent of Alzheimer | 霍夫曼-拉罗奇有限公司 | 2016-08-24 | — | — | CN | disclosed |
| CN-104411709-A | Imidazo [2,1]thiazol-3-one derivatives useful as diagnostic agents for alzheimer's disease | HOFFMANN LA ROCHE | 2015-03-11 | — | — | CN | disclosed |