Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | LIPE | Q05469 | 1/20 | 0.36 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GRM5 | P41594 | 6/20 | 0.34 |
| ▸ | SYK | P43405 | 2/20 | 0.34 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19483214 | 0.80 | HCAR2 (0.35) | HCAR2MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL26957589 | 0.78 | NOTUM (0.51) | ALOX15TSHRLIPEMEN1KMT2A | |
| SCHEMBL432934 | 0.77 | HCAR2 (0.44) | ALOX15HCAR2MEN1KMT2AKDM4E | |
| SCHEMBL28189368 | 0.75 | HCAR2 (0.38) | HCAR2MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL5264575 | 0.72 | RAB9A (0.39) | ALOX15TSHRKDM4EALDH1A1 | |
| SCHEMBL491229 | 0.71 | RAB9A (0.54) | ALOX15TSHRLIPEMEN1KMT2A | |
| SCHEMBL13896967 | 0.71 | SMN1; SMN2 (0.38) | ALOX15TSHRMEN1KMT2AALDH1A1 | |
| SCHEMBL8861880 | 0.69 | CA12 (0.47) | ALOX15TSHRMEN1KMT2AALDH1A1 | |
| SCHEMBL15161225 | 0.69 | ALDH1A1 (0.51) | ALOX15TSHRLIPEMEN1KMT2A | |
| SCHEMBL18019553 | 0.69 | MAP3K5 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103396399-B | Nitrogenated aromatic 6-membered ring derivative, and pharmaceutical agent comprising same | DAIICHI SANKYO CO LTD | 2015-04-29 | — | — | CN | disclosed |