Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | TYR | P14679 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.48 |
| ▸ | KIF11 | P52732 | 2/20 | 0.48 |
| ▸ | BCHE | P06276 | 2/20 | 0.48 |
| ▸ | ACHE | P22303 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.44 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL424728 | 0.89 | TSHR (0.73) | TSHRLMNATYRALDH1A1HDAC1 | |
| Formaldehyde SCHEMBL332381 | 0.86 | LMNA (0.84) | TSHRLMNATYRALDH1A1HDAC1 | |
| Formaldehyde SCHEMBL22263465 | 0.82 | LMNA (0.76) | TSHRLMNATYRALDH1A1HDAC1 | |
| Hydrogen Peroxide SCHEMBL28677809 | 0.81 | LMNA (0.71) | TSHRLMNATYRALDH1A1HDAC1 | |
| SCHEMBL16241997 | 0.80 | TSHR (0.55) | TSHRLMNATYRALDH1A1HDAC1 | |
| SCHEMBL52644 | 0.80 | TSHR (0.55) | TSHRLMNATYRALDH1A1HDAC1 | |
| SCHEMBL55222 | 0.80 | TSHR (0.55) | TSHRLMNATYRALDH1A1HDAC1 | |
| SCHEMBL3423876 | 0.79 | KIF11 (0.70) | TSHRLMNATYRALDH1A1HDAC1 | |
| SCHEMBL26915 | 0.79 | KIF11 (0.70) | TSHRLMNATYRALDH1A1HDAC1 | |
| Formaldehyde SCHEMBL22558111 | 0.79 | GABRA1 (0.58) | TSHRLMNATYRALDH1A1BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104603118-A | Carboxamide or sulfonamide substituted thiazoles and related derivatives as modulators of the orphan nuclear receptor ROR γ | PHENEX PHARMACEUTICALS AG | 2015-05-06 | — | — | CN | disclosed |