Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | CCR5 | P51681 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | MITF | O75030 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 2/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28005646 | 0.80 | MEN1 (0.56) | ALDH1A1LMNANPC1MEN1KMT2A | |
| SCHEMBL28005693 | 0.79 | MAPT (0.59) | ALDH1A1LMNANPC1RAB9AMAPT | |
| SCHEMBL28005399 | 0.78 | HSD11B1 (0.69) | ALDH1A1LMNANPC1MEN1KMT2A | |
| SCHEMBL28005275 | 0.76 | NFE2L2 (0.65) | ALDH1A1LMNANPC1MEN1KMT2A | |
| SCHEMBL3039038 | 0.73 | LMNA (0.51) | ALDH1A1LMNANPC1MEN1KMT2A | |
| SCHEMBL30969584 | 0.73 | MAPT (0.59) | ALDH1A1LMNANPC1MEN1KMT2A | |
| SCHEMBL28005280 | 0.72 | ALDH1A1 (0.54) | ALDH1A1LMNAMEN1KMT2AMAPT | |
| SCHEMBL28005648 | 0.72 | POLB (0.61) | ALDH1A1LMNANPC1MEN1KMT2A | |
| SCHEMBL309636 | 0.70 | MAPT (0.57) | ALDH1A1LMNANPC1MEN1KMT2A | |
| SCHEMBL29508979 | 0.70 | MAPT (0.57) | ALDH1A1LMNANPC1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104592032-A | Asymmetric mono-carbonyl curcumin analogues having 2-nitro unilateral substitute and application of analogues | UNIV WENZHOU MEDICAL | 2015-05-06 | — | — | CN | disclosed |