Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 2/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.46 |
| ▸ | MIF | P14174 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | HTR2B | P41595 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.42 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.40 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | DRD1 | P21728 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2795927 | 1.00 | ADRB1 (0.46) | ADRB1ADRA1AMIFHTR2AHTR2B | |
| SCHEMBL2575001 | 1.00 | ADRB1 (0.46) | ADRB1ADRA1AMIFHTR2AHTR2B | |
| SCHEMBL15687585 | 0.79 | ALDH1A1 (0.42) | SLC6A3GAASLC6A4ALDH1A1CYP3A4 | |
| SCHEMBL20483470 | 0.79 | AOC3 (0.42) | ADRB1HTR2BADRB2ADRB3SLC6A4 | |
| SCHEMBL858114 | 0.79 | AOC3 (0.42) | KDM4ESLC6A4CA12CA2CA9 | |
| SCHEMBL18272384 | 0.79 | AOC3 (0.42) | ADRB1HTR2BADRB2ADRB3SLC6A4 | |
| SCHEMBL16943864 | 0.79 | AOC3 (0.42) | ADRB1HTR2BADRB2ADRB3SLC6A4 | |
| SCHEMBL2053885 | 0.78 | CA1 (0.39) | DRD3ALDH1A1CA2CA9 | |
| SCHEMBL2025338 | 0.78 | CA1 (0.39) | DRD3ALDH1A1CA2CA9 | |
| SCHEMBL2800774 | 0.78 | CA1 (0.39) | DRD3ALDH1A1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130096337-A1 | Process for Preparation of Optically Active Compounds using Transfer Hydrogenation | NOVARTIS AG (CH) | 2013-04-18 | — | — | US | claimed |
| US-8415508-B2 | Process for the preparation of optically active compounds using transfer hydrogenation | NOVARTIS AG (CH) | 2013-04-09 | — | — | US | claimed |
| US-20100168229-A1 | Process for the preparation of optically active compounds using transfer hydrogenation | NOVARTIS AG (CH) | 2010-07-01 | — | — | US | claimed |
| US-8637713-B2 | Process for preparation of optically active compounds using transfer hydrogenation | NOVARTIS AG (CH) | 2014-01-28 | — | — | US | disclosed |
| US-20130096337-A1 | Process for Preparation of Optically Active Compounds using Transfer Hydrogenation | NOVARTIS AG (CH) | 2013-04-18 | — | — | US | disclosed |
| US-8415508-B2 | Process for the preparation of optically active compounds using transfer hydrogenation | NOVARTIS AG (CH) | 2013-04-09 | — | — | US | disclosed |
| US-20100168229-A1 | Process for the preparation of optically active compounds using transfer hydrogenation | NOVARTIS AG (CH) | 2010-07-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130096337-A1 | Process for Preparation of Optically Active Compounds using Transfer Hydrogenation | SPR, ACHE, QDPR | ADRB1 676/4885ADRA1A 787/4885MIF 3942/4885 |
| US-20100168229-A1 | Process for the preparation of optically active compounds using transfer hydrogenation | SPR, ACHE, QDPR | ADRB1 549/4885ADRA1A 723/4885MIF 4039/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.