SCHEMBL28007133

SCHEMBL28007133

CC(=O)N(C1CC1)C1CCN(OC(=O)C(C)(C)C)CC1

nearest known ligand 0.34

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
GPR119 Q8TDV5 20/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27679204 0.83 VNN1 (0.35)
SCHEMBL28253996 0.83 GPR119 (0.32) GPR119
SCHEMBL27987957 0.83 HTR2A (0.38) GPR119
SCHEMBL28023308 0.80 ACKR3 (0.37) GPR119
SCHEMBL28291375 0.78 OPRK1 (0.34)
SCHEMBL28965080 0.75 MCHR1 (0.33) GPR119
SCHEMBL3751065 0.75 GPR119 (0.56) GPR119
SCHEMBL27725144 0.75 OPRK1 (0.38)
SCHEMBL27643661 0.75 HPGD (0.36)
SCHEMBL28866127 0.75 DDB1 (0.35)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102459251-B Compounds with two fused bicyclic heteroaryl moieties as modulators of leukotriene a4 hydrolase JANSSEN PHARMACEUTICA NV 2015-05-20 CN disclosed