Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACKR3 | P25106 | 1/20 | 0.37 |
| ▸ | CBX7 | O95931 | 2/20 | 0.34 |
| ▸ | CDYL2 | Q8N8U2 | 2/20 | 0.34 |
| ▸ | CDYL | Q9Y232 | 2/20 | 0.34 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.34 |
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.32 |
| ▸ | CDY1; CDY1B | Q9Y6F8 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28124717 | 0.88 | ACKR3 (0.31) | ACKR3 | |
| SCHEMBL27735101 | 0.85 | GPR119 (0.31) | GPR119 | |
| SCHEMBL27987957 | 0.83 | HTR2A (0.38) | GPR119 | |
| SCHEMBL28007133 | 0.80 | GPR119 (0.34) | GPR119 | |
| SCHEMBL28267108 | 0.80 | MCHR1 (0.37) | TRPV4GPR119 | |
| SCHEMBL28253996 | 0.79 | GPR119 (0.32) | GPR119 | |
| SCHEMBL28291375 | 0.78 | OPRK1 (0.34) | ALDH1A1 | |
| SCHEMBL27679204 | 0.77 | VNN1 (0.35) | — | |
| SCHEMBL19652207 | 0.76 | ACKR3 (0.41) | ACKR3CBX7CDYL2CDYLTRPV4 | |
| SCHEMBL15410506 | 0.75 | GPR119 (0.52) | GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103459388-B | Novel furanone derivative | CARNA BIOSCIENCES, INC. (JP) | 2015-11-25 | — | — | CN | disclosed |
| CN-104860891-A | Arylaminopyrimidine compound and use thereof and pharmaceutical composition and medicinal composition prepared from arylaminopyrimidine compound | SHANGHAI HAIYAN PHARMACEUTICAL TECHNOLOGY CO LTD | 2015-08-26 | — | — | CN | disclosed |