Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.30 |
| ▸ | ENO1 | P06733 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27725144 | 0.97 | OPRK1 (0.38) | OPRK1KMT2AALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL28253996 | 0.95 | GPR119 (0.32) | HSD11B1L3MBTL3 | |
| SCHEMBL28253864 | 0.88 | DDB1 (0.34) | — | |
| SCHEMBL28965080 | 0.87 | MCHR1 (0.33) | HSD11B1 | |
| SCHEMBL28866127 | 0.83 | DDB1 (0.35) | — | |
| SCHEMBL27679204 | 0.81 | VNN1 (0.35) | LMNAMAPTHSD11B1 | |
| SCHEMBL27926085 | 0.80 | HSD11B1 (0.34) | ALDH1A1HSD11B1 | |
| SCHEMBL27770770 | 0.79 | HTR2A (0.34) | ALDH1A1LMNA | |
| SCHEMBL28820105 | 0.79 | PIM1 (0.32) | L3MBTL3ENO1 | |
| SCHEMBL28023308 | 0.78 | ACKR3 (0.37) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109563043-A | SUBSTITUTED PYRIDINES AS INHIBITORS OF DNMT1 | 葛兰素史密斯克莱知识产权发展有限公司 | 2019-04-02 | — | — | CN | disclosed |