SCHEMBL28008659

SCHEMBL28008659

O=C(Cc1ccccc1)OOCCCc1ccccc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.53
MAPK1 P28482 2/20 0.49
ALDH1A1 P00352 2/20 0.49
TDP1 Q9NUW8 2/20 0.49
L3MBTL1 Q9Y468 1/20 0.49
SMN1; SMN2 Q16637 3/20 0.47
NPC1 O15118 2/20 0.47
RAB9A P51151 2/20 0.47
FFAR1 O14842 1/20 0.47
RECQL P46063 1/20 0.47
GAA P10253 1/20 0.47
HPGD P15428 1/20 0.47
PAM P19021 1/20 0.47
IDO1 P14902 1/20 0.47
HDAC3 O15379 1/20 0.47
ADRA1A P35348 1/20 0.47
HDAC4 P56524 1/20 0.47
SLC6A3 Q01959 1/20 0.47
HDAC1 Q13547 1/20 0.47
HDAC7 Q8WUI4 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9065264 0.85 TSHR (0.49) MAPK1ALDH1A1TDP1L3MBTL1SMN1; SMN2
SCHEMBL18554127 0.83 MEN1 (0.48) LMNAMAPK1ALDH1A1L3MBTL1SMN1; SMN2
SCHEMBL3396096 0.82 LMNA (0.66) LMNAMAPK1ALDH1A1TDP1L3MBTL1
SCHEMBL5668789 0.81 LMNA (0.54) LMNAMAPK1ALDH1A1TDP1SMN1; SMN2
SCHEMBL26698258 0.79 TSHR (0.50) LMNAMAPK1ALDH1A1TDP1L3MBTL1
Benzene SCHEMBL9407299 0.79 ALDH1A1 (0.65) MAPK1ALDH1A1L3MBTL1SMN1; SMN2PAM
SCHEMBL664857 0.79 ALDH1A1 (0.65) MAPK1ALDH1A1L3MBTL1SMN1; SMN2PAM
SCHEMBL6625857 0.78 ALDH1A1 (0.66) LMNAMAPK1ALDH1A1TDP1L3MBTL1
SCHEMBL2877979 0.77 ALDH1A1 (0.63) MAPK1ALDH1A1L3MBTL1SMN1; SMN2PAM
SCHEMBL28392150 0.77 MAPK1 (0.46) MAPK1ALDH1A1TDP1L3MBTL1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104412441-A Nonaqueous electrolyte solution and nonaqueous electrolyte battery using same MITSUBISHI CHEM CORP 2015-03-11 CN disclosed