Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | PAM | P19021 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | PDE4A | P27815 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18554127 | 0.95 | MEN1 (0.48) | TSHRL3MBTL1ALDH1A1MAPK1CYP3A4 | |
| SCHEMBL28008659 | 0.85 | LMNA (0.53) | TSHRL3MBTL1ALDH1A1MAPK1TDP1 | |
| SCHEMBL456516 | 0.83 | ALDH1A1 (0.59) | TSHRL3MBTL1ALDH1A1MAPK1TDP1 | |
| SCHEMBL26698258 | 0.81 | TSHR (0.50) | TSHRL3MBTL1ALDH1A1MAPK1TDP1 | |
| SCHEMBL27672935 | 0.81 | ALDH1A1 (0.58) | TSHRL3MBTL1ALDH1A1MAPK1TDP1 | |
| Hydrochloric Acid SCHEMBL27576461 | 0.81 | L3MBTL1 (0.58) | TSHRL3MBTL1ALDH1A1MAPK1TDP1 | |
| SCHEMBL27484985 | 0.80 | ALDH1A1 (0.56) | TSHRL3MBTL1ALDH1A1MAPK1TDP1 | |
| SCHEMBL27803277 | 0.79 | ALDH1A1 (0.53) | ALDH1A1TDP1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL28638406 | 0.78 | TDP1 (0.54) | TSHRALDH1A1TDP1 | |
| SCHEMBL539127 | 0.78 | ALDH1A1 (0.58) | TSHRL3MBTL1ALDH1A1MAPK1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5508372-A | POLYMERIZATION WITH HYDROXY ACRYLATE RESINS AND OPTIONAL POLYETHERS, POLYESTERS AND POLYCARBONATES; MOISTURE CURABLE | BAYER AKTIENGESELLSCHAFT (DE) | 1996-04-16 | — | — | US | disclosed |
| EP-0171976-B1 | CRYSTALLINE 1-BUTENE POLYMER COMPOSITION | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1989-10-18 | — | — | EP | disclosed |
| EP-0149356-B1 | LAMINATED STRUCTURE HAVING POST-CHLORINATED ADHESIVE OLEFIN RESIN LAYER | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1988-09-07 | — | — | EP | disclosed |
| US-4382114-A | POLYESTERPOLYOL, ISOCYANATE | BAYER AKTIENGESELLSCHAFT (DE) | 1983-05-03 | — | — | US | disclosed |
| US-4291135-A | CROSSLINKABLE ACRYLATE COPOLYMERS, ALKYD RESINS AND POLYSILOXANES SUITABLE AS LACQUERS | BAYER AKTIENGESELLSCHAFT (DE) | 1981-09-22 | — | — | US | disclosed |