Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MYC | P01106 | 1/20 | 0.38 |
| ▸ | WDR5 | P61964 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5930632 | 0.81 | ALDH1A1 (0.69) | ALDH1A1TDP1L3MBTL1HSD17B10LMNA | |
| SCHEMBL2226447 | 0.80 | DRD2 (0.53) | L3MBTL1LMNAMAPTKMT2ARAB9A | |
| SCHEMBL4727339 | 0.80 | ALDH1A1 (0.46) | ALDH1A1TDP1L3MBTL1HSD17B10LMNA | |
| SCHEMBL28008732 | 0.80 | ALDH1A1 (0.68) | ALDH1A1TDP1L3MBTL1HSD17B10LMNA | |
| SCHEMBL1557834 | 0.77 | LMNA (0.47) | ALDH1A1TDP1L3MBTL1LMNAMAPT | |
| SCHEMBL5539775 | 0.76 | ALDH1A1 (0.40) | ALDH1A1TDP1L3MBTL1HSD17B10LMNA | |
| SCHEMBL28299739 | 0.75 | KDM4E (0.56) | ALDH1A1HSD17B10LMNAMAPTHPGD | |
| SCHEMBL285339 | 0.75 | — | — | |
| SCHEMBL28619008 | 0.74 | KDM4E (0.45) | ALDH1A1TDP1L3MBTL1HSD17B10LMNA | |
| SCHEMBL11341609 | 0.73 | KDM4E (0.45) | LMNAKMT2ARAB9AHPGDPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109867666-B | Aromatic acetamide compound containing isothiazole ring and application thereof | 沈阳中化农药化工研发有限公司 | 2021-09-07 | — | — | CN | disclosed |
| CN-109867666-A | A kind of fragrant acetamides of the ring containing isothiazole and application thereof | 沈阳中化农药化工研发有限公司 | 2019-06-11 | — | — | CN | disclosed |
| CN-104650063-B | A kind of 2,4 dimethyl oxazoline base acrylonitrile compounds and its application | 沈阳中化农药化工研发有限公司 | 2017-11-28 | — | — | CN | disclosed |
| CN-104649997-B | 2,4-dimethylthiazole acrylonitrile compound and application thereof | 沈阳中化农药化工研发有限公司 | 2017-05-10 | — | — | CN | disclosed |
| CN-104649997-A | 2,4-dimethylthiazole acrylonitrile compound and application thereof | SINOCHEM CORP | 2015-05-27 | — | — | CN | disclosed |
| CN-104650063-A | 2,4-dimethyl oxazole acrylonitrile compound and application thereof | SINOCHEM CORP | 2015-05-27 | — | — | CN | disclosed |