Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 6/20 | 0.51 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.48 |
| ▸ | HTR3A | P46098 | 3/20 | 0.47 |
| ▸ | HTR2A | P28223 | 2/20 | 0.46 |
| ▸ | HTR6 | P50406 | 2/20 | 0.46 |
| ▸ | DHFR | P00374 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28070389 | 0.79 | HRH4 (0.52) | HRH4ADRA2CDHFR | |
| SCHEMBL28120724 | 0.77 | DHFR (0.52) | HRH4ADRA2CDHFR | |
| SCHEMBL28324074 | 0.74 | DHFR (0.65) | HRH4DHFR | |
| SCHEMBL13769597 | 0.74 | HTR3A (0.54) | HRH4ADRA2CHRH3HTR3AHTR2A | |
| SCHEMBL2197477 | 0.72 | HTR6 (0.56) | HRH4ADRA2CHTR3AHTR2AHTR6 | |
| SCHEMBL30463625 | 0.72 | DHFR (0.56) | HRH4ADRA2CHRH3HTR3ADHFR | |
| SCHEMBL2197147 | 0.72 | HTR6 (0.56) | HRH4ADRA2CHTR3AHTR2AHTR6 | |
| SCHEMBL28311804 | 0.71 | ADRA2C (0.53) | HRH4ADRA2CHRH3HTR3AHTR6 | |
| SCHEMBL12932459 | 0.71 | HTR2A (0.60) | HRH4HRH3HTR2AHTR6 | |
| SCHEMBL29414481 | 0.70 | PIK3CD (0.49) | HRH4ADRA2CHRH3DHFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104582703-A | H4 receptor inhibitors for treating tinnitus | SENSORION | 2015-04-29 | — | — | CN | disclosed |