Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.37 |
| ▸ | RAB9A | P51151 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | PDK1 | Q15118 | 2/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.36 |
| ▸ | PDK3 | Q15120 | 2/20 | 0.36 |
| ▸ | PDK4 | Q16654 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 6/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.35 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17201891 | 0.88 | NPC1 (0.42) | NPC1RAB9ALMNAMEN1KMT2A | |
| SCHEMBL7785471 | 0.84 | MEN1 (0.51) | NPC1RAB9ALMNAMEN1KMT2A | |
| SCHEMBL28556638 | 0.83 | NPC1 (0.40) | NPC1RAB9ALMNAMEN1KMT2A | |
| SCHEMBL26578933 | 0.81 | NPC1 (0.51) | NPC1RAB9ALMNAMEN1KMT2A | |
| SCHEMBL45835 | 0.81 | NPC1 (0.54) | NPC1RAB9ALMNAMEN1KMT2A | |
| SCHEMBL5834566 | 0.81 | ALOX5 (0.41) | NPC1RAB9ALMNAMEN1KMT2A | |
| SCHEMBL9010899 | 0.81 | NPC1 (0.55) | NPC1RAB9ALMNAPDK1PDK2 | |
| SCHEMBL30383298 | 0.81 | MAPT (0.41) | NPC1RAB9ALMNAMEN1KMT2A | |
| SCHEMBL7783973 | 0.81 | AMY1A (0.42) | NPC1RAB9ALMNAPDK1PDK2 | |
| SCHEMBL29602456 | 0.81 | AMY1A (0.42) | NPC1RAB9ALMNAPDK1PDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3161528-B1 | COMPOSITION FOR THE MANUFACTURE OF AN OPHTALMIC LENS COMPRISING AN UV-ABSORBER AND AN ANTI-YELLOWING ADDITIVE | ESSILOR INT (FR) | 2020-03-04 | — | — | EP | disclosed |
| US-10370520-B2 | Composition for the manufacture of an ophthalmic lens comprising an UV-absorber and an anti-yellowing additive | ESSILOR INTERNATIONAL (FR) | 2019-08-06 | — | — | US | disclosed |
| US-20170121498-A1 | Composition for the Manufacture of an Ophthalmic Lens Comprising an UV-Absorber and an Anti-Yellowing Additive | ESSILOR INTERNATIONAL (FR) | 2017-05-04 | — | — | US | disclosed |
| EP-3161528-A1 | COMPOSITION FOR THE MANUFACTURE OF AN OPHTALMIC LENS COMPRISING AN UV-ABSORBER AND AN ANTI-YELLOWING ADDITIVE | Essilor International (Compagnie Générale D'Optique) (FR) | 2017-05-03 | — | — | EP | disclosed |
| EP-2960687-B1 | COMPOSITION FOR THE MANUFACTURE OF AN OPHTALMIC LENS COMPRISING AN UV-ABSORBER AND AN ANTI-YELLOWING ADDITIVE | ESSILOR INT (FR) | 2016-09-21 | — | — | EP | disclosed |
| EP-2960687-A1 | Composition for the manufacture of an ophtalmic lens comprising an uv-absorber and an anti-yellowing additive | ESSILOR INTERNATIONAL (COMPAGNIE GENERALE D'OPTIQUE) (FR) | 2015-12-30 | — | — | EP | disclosed |
| US-20100201939-A1 | PLASTIC LENS AND METHOD OF MANUFACTURING THE SAME | HOYA CORPORATION (JP) | 2010-08-12 | — | — | US | disclosed |
| EP-2172792-A1 | PLASTIC LENS AND METHOD OF MANUFACTURING THE SAME | Hoya Corporation (JP) | 2010-04-07 | — | — | EP | disclosed |
| EP-1085349-B1 | Plastic lenses having good ultraviolet absorbability, and method for the production thereof | HOYA CORP (JP) | 2006-06-28 | — | — | EP | disclosed |
| US-6448304-B1 | POLYURETHANE, POLYTHIOURETHANE OR DIETHYLENE GLYCOL BISALLYLCARBONATE POLYMER; DIPPING IN SOLUTION CONTAINING A DIBENZOYLMETHANE OR A BENZOTRIZOLE COMPOUND; PLASTIC LENS FOR SPECTACLES WHICH ABSORBS ULTRAVIOLET RAYS; LOW YELLOWNESS | HOYA CORPORATION (JP) | 2002-09-10 | — | — | US | disclosed |
| EP-1144391-A1 | ONE-POT PROCESS FOR THE PREPARATION OF 5-SULFONYL-SUBSTITUTED BENZOTRIAZOLES | Ciba SC Holding AG (CH) | 2001-10-17 | — | — | EP | disclosed |
| EP-1085349-A2 | Plastic lenses having good ultraviolet absorbability, and method for the production thereof | HOYA CORPORATION (JP) | 2001-03-21 | — | — | EP | disclosed |
| WO-2000043376-A1 | ONE-POT PROCESS FOR THE PREPARATION OF 5-SULFONYL-SUBSTITUTED BENZOTRIAZOLES | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2000-07-27 | — | — | WO | disclosed |
| US-6040455-A | REACTING A HALOBENZOTRIAZOLE COMPOUND WITH ALIPHATIC, PHENYLALKYL OR ARYL MERCAPTAN COMPOUND TO FORM 5-THIO SUBSTITUTED BENZOTRIAZOLE, OXIDIZING WITH HYDROGEN PEROXIDE TO FOR 5-SULFONE SUBSTITUED BENZOTRIAZOLE COMPOUND | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2000-03-21 | — | — | US | disclosed |