SCHEMBL2801370

SCHEMBL2801370

NC(=O)N1C(=O)C=CC1=O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.43
MAPK1 P28482 3/20 0.43
TSHR P16473 1/20 0.43
SCN4A P35499 1/20 0.43
SCN5A Q14524 1/20 0.43
SCN9A Q15858 1/20 0.43
BCHE P06276 1/20 0.37
ACHE P22303 1/20 0.37
MGLL Q99685 6/20 0.36
GSK3A P49840 2/20 0.36
GSK3B P49841 2/20 0.36
ALDH1A1 P00352 5/20 0.34
MAPT P10636 4/20 0.34
NPSR1 Q6W5P4 4/20 0.34
HPGD P15428 3/20 0.34
HTT P42858 2/20 0.34
BLM P54132 3/20 0.33
FAAH O00519 3/20 0.33
DDAH1 O94760 1/20 0.33
NSD2 O96028 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL711961 0.75 NSD2 (0.41) LMNAMAPK1MGLLGSK3AGSK3B
SCHEMBL15386143 0.74 MGLL (0.35) LMNAMAPK1MGLLGSK3AGSK3B
SCHEMBL15301140 0.74 TDP1 (0.32) LMNAMGLLGSK3AGSK3BALDH1A1
SCHEMBL317849 0.73 DDAH1 (0.39) LMNAMAPK1MGLLGSK3AGSK3B
SCHEMBL22092274 0.71 PTGS1 (0.33) LMNAMAPK1MGLLALDH1A1MAPT
SCHEMBL720720 0.71 MGLL (0.43) LMNAMAPK1MGLLGSK3AGSK3B
SCHEMBL28570540 0.71 P2RX4 (0.37) LMNAMAPK1MGLLGSK3AGSK3B
SCHEMBL1286137 0.70 GSK3A (0.32) TSHRMGLLGSK3AGSK3BDDAH1
SCHEMBL8607093 0.70 MGLL (0.39) LMNAMAPK1MGLLGSK3AGSK3B
SCHEMBL3547009 0.67 KDM4E (0.33) LMNAMAPK1TSHRSCN4ASCN5A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 183 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117567979-B High-temperature-resistant reversible self-repairing UV and moisture dual-curing three-proofing adhesive 信泰永合(烟台)新材料有限公司 2024-05-28 CN claimed
CN-117986068-A High-stability emulsion explosive and preparation method thereof 四川省南部永生化工有限责任公司 2024-05-07 CN claimed
CN-117567979-A High-temperature-resistant reversible self-repairing UV and moisture dual-curing three-proofing adhesive 信泰永合(烟台)新材料有限公司 2024-02-20 CN claimed
CN-117447734-A PU graphene waterproof wet-through film and preparation method thereof 安徽达钰新材料科技有限公司 2024-01-26 CN claimed
CN-114989652-B Antibacterial coating for surface protection of stainless steel structure 佛山市建春友金属科技有限公司 2023-04-07 CN claimed
CN-109432420-B Preparation method of nano-particles 中国人民解放军东部战区总医院 2022-11-18 CN claimed
CN-114989652-A Antibacterial coating for surface protection of stainless steel structure 佛山市建春友金属科技有限公司 2022-09-02 CN claimed
CN-114944240-A Wire harness body applied to automobile and preparation method thereof 扬州宏联汽车零部件有限公司 2022-08-26 CN claimed
CN-109395079-B Multifunctional nano probe and preparation method and application thereof 中国人民解放军东部战区总医院 2021-07-23 CN claimed
CN-109957076-B Mud-resistant slump-retaining polycarboxylate superplasticizer and preparation method thereof 江苏万邦新材料科技有限公司 2021-06-04 CN claimed
US-20100167081-A1 RESIN COMPOSITION CONTAINING CATALYST PRECURSOR FOR ELECTROLESS PLATING IN FORMING ELECTRO-MAGNETIC SHIELDING LAYER, METHOD OF FORMING METALLIC PATTERN USING THE SAME, AND METALLIC PATTERN FORMED BY THE SAME METHOD LG CHEM, LTD. (KR) 2010-07-01 US claimed
EP-2029095-A2 PROCESS FOR STRAIGHTENING KERATIN FIBRES WITH A HEATING MEANS AND DENATURING AGENTS L'Oréal (FR) 2009-03-04 EP claimed
WO-2007135297-A2 PROCESS FOR STRAIGHTENING KERATIN FIBRES WITH A HEATING MEANS AND DENATURING AGENTS L'OREAL (FR) 2007-11-29 WO claimed
US-20060127337-A1 Process for relaxing keratin fibres L'OREAL (FR) 2006-06-15 US claimed
EP-1661551-A2 Method of straightening keratin fibres with heating means and a denaturant agent L'OREAL (FR) 2006-05-31 EP claimed
US-4782133-A MALEIC ANHYDRIDE AND DIAMINE, CATALYTIC CYCLODEHYDRATION DSM RESINS B.V. (NL) 1988-11-01 US claimed
US-4684706-A COPOLYMER OF BISMALEIMIDE-MALEIMIDE-AMIDE AND MALEIC ANHYDRIDE-CHEMICAL AND HEAT RESISTANCE DSM RESINS B.V. (NL) 1987-08-04 US claimed
EP-0135964-B1 COMPOSITIONS CONTAINING MALEIMIDE-AMIDE COMPOUNDS AS WELL AS THE PREPARATION AND APPLICATION THEREOF DSM RESINS B.V. (NL) 1987-04-01 EP claimed
US-4582883-A CURABLE TO CHEMICAL, HEAT RESISTANT THERMOSETTING RESIN DSM RESINS B.V. (NL) 1986-04-15 US claimed
EP-0135964-A2 Compositions containing maleimide-amide compounds as well as the preparation and application thereof DSM RESINS B.V. (NL) 1985-04-03 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060127337-A1 Process for relaxing keratin fibres KRT18, TPM4, MYLK LMNA 227/4885MAPK1 2198/4885TSHR 3657/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.