SCHEMBL317849

SCHEMBL317849

O=C(O)N1C(=O)C=CC1=O

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DDAH1 O94760 1/20 0.39
NSD2 O96028 1/20 0.39
G6PD P11413 1/20 0.39
KEAP1 Q14145 1/20 0.39
NFE2L2 Q16236 1/20 0.39
MGLL Q99685 7/20 0.38
GSK3A P49840 3/20 0.38
GSK3B P49841 3/20 0.38
PTGS1 P23219 5/20 0.37
PTGS2 P35354 5/20 0.37
FAAH O00519 2/20 0.35
ALDH1A1 P00352 4/20 0.33
HSP90AA1 P07900 4/20 0.33
NPSR1 Q6W5P4 3/20 0.33
BLM P54132 2/20 0.33
PKM P14618 2/20 0.33
TDP1 Q9NUW8 2/20 0.33
ATM Q13315 2/20 0.33
HPGD P15428 2/20 0.33
TLR9 Q9NR96 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL711961 0.78 NSD2 (0.41) DDAH1NSD2G6PDKEAP1NFE2L2
SCHEMBL2801370 0.73 LMNA (0.43) DDAH1NSD2G6PDKEAP1NFE2L2
SCHEMBL11880206 0.73 MGLL (0.36) DDAH1NSD2G6PDKEAP1NFE2L2
SCHEMBL28570540 0.73 P2RX4 (0.37) DDAH1NSD2G6PDKEAP1NFE2L2
SCHEMBL720720 0.73 MGLL (0.43) DDAH1NSD2G6PDKEAP1NFE2L2
SCHEMBL7110683 0.73 DDAH1 (0.34) DDAH1NSD2G6PDKEAP1NFE2L2
SCHEMBL1321593 0.69 P2RX4 (0.57) MGLLGSK3AGSK3BALDH1A1HSP90AA1
SCHEMBL4761585 0.69 MGLL (0.35) DDAH1NSD2G6PDKEAP1NFE2L2
SCHEMBL284850 0.69 MGLL (0.33) DDAH1NSD2G6PDKEAP1NFE2L2
SCHEMBL10586150 0.69 MGLL (0.38) DDAH1NSD2G6PDKEAP1NFE2L2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 337 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117304811-A High-functionality vegetable oil-based UV (ultraviolet) light-cured resin as well as preparation method and application thereof 佛山科学技术学院 2023-12-29 CN claimed
CN-117165366-A Universal UV light-cured modified vegetable oil resin and synthetic method and application thereof 佛山科学技术学院 2023-12-05 CN claimed
EP-2244718-B1 PEPTIDES HAVING BINDING AFFINITY TO AN ANTIBODY WHICH RECOGNIZES AN EPITOPE ON AN 1 LOOP 2 OR 2 LOOP 1 OF AN ADRENORECEPTOR MDC MAX-DELBRÜCK-CENTRUM FÜR MOLEKULARE MEDIZIN BERLIN - BUCH (DE) 2017-06-07 EP claimed
US-20130302292-A1 PEPTIDES HAVING BINDING AFFINITY TO AN ANTIBODY WHICH RECOGNIZES AN EPITOPE ON AN ALPHA1 LOOP 2 OR BETA2 LOOP 1 OF AN ADRENORECEPTOR FRESENIUS MEDICAL CARE DEUTSCHLAND GMBH (DE) 2013-11-14 US claimed
US-8058019-B2 Method for assaying antibodies in body fluids by immune reaction with glycoprotein 2 (GP2) from zymogenic granules of the pancreas for the differential diagnosis of inflammatory intestinal diseases and chronic pancreatitis GA GENERIC ASSAYS GMBH (DE) 2011-11-15 US claimed
US-20110104226-A1 PEPTIDES HAVING BINDING AFFINITY TO AN ANTIBODY WHICH RECOGNIZES AN EPITOPE ON AN A1 LOOP 2 OR BETA2 LOOP 1 OF AN ADRENORECEPTOR FRESENIUS MEDICAL CARE DEUTSCHLAND GMBH (DE) 2011-05-05 US claimed
EP-2244718-A2 PEPTIDES HAVING BINDING AFFINITY TO AN ANTIBODY WHICH RECOGNIZES AN EPITOPE ON AN 1 LOOP 2 OR 2 LOOP 1 OF AN ADRENORECEPTOR Mdc Max-Delbrück-Centrum Für Molekulare Medizin Berlin - Buch (DE) 2010-11-03 EP claimed
US-20100266686-A1 ANTI-AMYLOID ANTIBODIES AND THEIR USE IN DIAGNOSIS AND THERAPY OF AMYLOID DISEASES HANS-KNOELL-INSTITUT FUER NATURSTOFFFORSCHUNG (DE) 2010-10-21 US claimed
US-20100184662-A1 METHOD FOR ASSAYING ANTIBODIES IN BODY FLUIDS BY IMMUNE REACTION WITH GLYCOPROTEIN 2 (GP2) FROM ZYMOGENIC GRANULES OF THE PANCREAS FOR THE DIFFERENTIAL DIAGNOSIS OF INFLAMMATORY INTESTINAL DISEASES AND CHRONIC PANCREATITIS GA GENERIC ASSAYS GMBH (DE) 2010-07-22 US claimed
WO-2010069570-A2 PEPTIDES AGAINST AUTOANTIBODIES ASSOCIATED WITH CRPS AND USE OF THESE PEPTIDES Max-Delbrück-Centrum für Molekulare Medizin (DE) 2010-06-24 WO claimed
US-7141691-B2 Protein-bound derivatives of platinum complexes containing cyclobutane1, 1-dicarboxyllate ligands KTB TUMORFORSCHUNGS GMBH (DE) 2006-11-28 US claimed
EP-1214350-B1 PEPTIDES FOR COMBATING THE AUTOANTIBODIES THAT ARE RESPONSIBLE FOR DILATATIVE CARDIOMYOPATHY (DCM) FRESENIUS MEDICAL CARE AFFINA (DE) 2006-09-06 EP claimed
US-20060089341-A1 Protein-bound derivatives of platinum complexes containing cyclobutane1,1-dicarboxyllate ligands KTB TUMORFORSCHUNGS GMBH (DE) 2006-04-27 US claimed
US-20060047140-A1 Process for producing polymerizable polybranched polyester DAINIPPON INK AND CHEMICALS, INC. (JP) 2006-03-02 US claimed
EP-1591451-A1 PEPTIDE CONJUGATE Keio University (JP) 2005-11-02 EP claimed
EP-1582548-A1 PROCESS FOR PRODUCING POLYMERIZABLE POLYBRANCHED POLYESTER DAINIPPON INK AND CHEMICALS, INC. (JP) 2005-10-05 EP claimed
US-20040087765-A1 Peptides, the production and use thereof for binding immunoglobulins FRESENIUS MEDICAL CARE AFFINA GMBH (DE) 2004-05-06 US claimed
US-20040023048-A1 Enhanced bonding layers on native oxide surfaces NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2004-02-05 US claimed
EP-0336856-B1 WITH MALEIMIDE GROUPS FUNCTIONALIZED AROMATIC POLYAMIDEIMIDES, PROCESS FOR THEIR PREPARATION AND THEIR USE FOR PREPARING CROSS-LINKED POLYMERS CIBA-GEIGY AG (CH) 1993-03-03 EP claimed
US-4131707-A POLYMALEIMIDES CIBA-GEIGY CORPORATION (US) 1978-12-26 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040087765-A1 Peptides, the production and use thereof for binding immunoglobulins IGSF11, FCGRT, F13A1 DDAH1 2002/4885NSD2 4779/4885G6PD 4162/4885
US-20060047140-A1 Process for producing polymerizable polybranched polyester ACSL4, ACSL1, HACL2 DDAH1 178/4885NSD2 3094/4885G6PD 2216/4885
US-20060089341-A1 Protein-bound derivatives of platinum complexes containing cyclobutane1,1-dicarboxyllate ligands DDB1, DCLRE1A, PDCD1LG2 DDAH1 712/4885NSD2 4262/4885G6PD 2604/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.