Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | TRPM5 | Q9NZQ8 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20079989 | 0.79 | LMNA (0.49) | LMNATP53TRPM5 | |
| SCHEMBL1068060 | 0.78 | LMNA (0.33) | LMNATP53TRPM5CHRNA7 | |
| SCHEMBL27304325 | 0.76 | TRPM5 (0.38) | TRPM5CHRNA7 | |
| SCHEMBL115421 | 0.76 | LMNA (0.40) | LMNATP53TRPM5CHRNA7 | |
| SCHEMBL8914255 | 0.75 | TRPM5 (0.34) | LMNATP53TRPM5CHRNA7 | |
| SCHEMBL6509518 | 0.74 | CYP2A6 (0.50) | — | |
| SCHEMBL9976426 | 0.74 | LMNA (0.39) | LMNATP53TRPM5RAB9ACHRNA7 | |
| SCHEMBL8179979 | 0.73 | CYP1A2 (0.44) | LMNATP53TRPM5RAB9A | |
| SCHEMBL13500632 | 0.71 | GAA (0.50) | LMNA | |
| SCHEMBL6236930 | 0.71 | CYP2A6 (0.53) | TRPM5RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105745210-B | Method for preparing the ketone derivatives of 8 (4 amino-benzene oxygen) 4H pyridos [2,3 B] pyrazine 3 | 癌症研究技术有限公司 | 2018-03-02 | — | — | CN | disclosed |
| CN-107417616-A | Methods and compositions for treating beta-thalassemia and sickle cell disease | 中央研究院 | 2017-12-01 | — | — | CN | disclosed |
| CN-107033164-A | Prepare the synthetic method of ecteinascidin compounds | 法马马有限公司 | 2017-08-11 | — | — | CN | disclosed |
| CN-106573951-A | Micro saponin analogue, synthesis and use thereof | 索隆-基特林癌症研究协会 | 2017-04-19 | — | — | CN | disclosed |
| CN-104010643-B | Methods and compositions for reducing body fat and adipocytes | 托普凯恩制药公司 | 2017-03-29 | — | — | CN | disclosed |
| CN-105246334-A | Macrolides and methods of making and using the same | HARVARD COLLEGE | 2016-01-13 | — | — | CN | disclosed |
| CN-105209015-A | Compositions and methods for local delivery of prostaglandins to subcutaneous fat | TOPOKINE THERAPEUTICS INC | 2015-12-30 | — | — | CN | disclosed |
| CN-103108642-B | RNA interference in cutaneous and fibrotic conditions | Lexie Pharmaceuticals (US) | 2015-09-23 | — | — | CN | disclosed |
| CN-102014897-B | Compound, compositions and its preparation method | SIGNUM BIOSCIENCES, INC. (US) | 2015-08-05 | — | — | CN | disclosed |
| CN-104640540-A | Enhanced anti-influenza agents coupled with anti-inflammatory activity | ACADEMIA SINICA | 2015-05-20 | — | — | CN | disclosed |