Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC18A3 | Q16572 | 3/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | NTMT1 | Q9BV86 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28014791 | 0.97 | SLC18A3 (0.43) | SLC18A3OPRK1OPRM1SMN1; SMN2MEN1 | |
| SCHEMBL12015487 | 0.77 | SLC18A3 (0.44) | SLC18A3OPRK1OPRM1MEN1ALDH1A1 | |
| SCHEMBL12015482 | 0.76 | SLC18A3 (0.43) | SLC18A3OPRK1OPRM1CHRNA7MEN1 | |
| SCHEMBL27919816 | 0.76 | CYP19A1 (0.40) | TSHRHTTSMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL27895229 | 0.76 | GSR (0.42) | SMN1; SMN2MEN1KMT2AHSD17B10DPP4 | |
| SCHEMBL1027856 | 0.75 | NTMT1 (0.36) | SLC18A3SMN1; SMN2ALDH1A1DPP4NTMT1 | |
| SCHEMBL27701856 | 0.75 | SLC18A3 (0.34) | SLC18A3ALDH1A1NTMT1L3MBTL1 | |
| SCHEMBL18398614 | 0.74 | LMNA (0.33) | TSHRSMN1; SMN2MEN1ALDH1A1KMT2A | |
| SCHEMBL27621632 | 0.74 | LMNA (0.33) | TSHRSMN1; SMN2MEN1ALDH1A1KMT2A | |
| SCHEMBL28064432 | 0.74 | LMNA (0.33) | TSHRSMN1; SMN2MEN1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102482203-B | Carbocyclic GLYT1 receptor antagonists | HOFFMANN LA ROCHE | 2015-06-03 | — | — | CN | disclosed |