Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.72 |
| ▸ | MAPT | P10636 | 5/20 | 0.72 |
| ▸ | MEN1 | O00255 | 4/20 | 0.72 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.72 |
| ▸ | THRB | P10828 | 2/20 | 0.72 |
| ▸ | RECQL | P46063 | 2/20 | 0.72 |
| ▸ | USP2 | O75604 | 1/20 | 0.72 |
| ▸ | POLB | P06746 | 1/20 | 0.72 |
| ▸ | PKM | P14618 | 1/20 | 0.72 |
| ▸ | APEX1 | P27695 | 1/20 | 0.72 |
| ▸ | BLM | P54132 | 1/20 | 0.72 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.72 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.53 |
| ▸ | GFER | P55789 | 2/20 | 0.53 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.52 |
| ▸ | TNF | P01375 | 1/20 | 0.52 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1027446 | 0.93 | KMT2A (0.61) | KMT2AMAPTMEN1TDP1THRB | |
| SCHEMBL1554060 | 0.87 | KMT2A (0.59) | KMT2AMAPTMEN1TDP1THRB | |
| SCHEMBL107833 | 0.87 | KMT2A (0.95) | KMT2AMAPTMEN1TDP1THRB | |
| SCHEMBL712251 | 0.85 | KDM4E (0.61) | KMT2AMAPTMEN1TDP1THRB | |
| Hydrochloric Acid SCHEMBL864766 | 0.85 | KMT2A (1.00) | KMT2AMAPTMEN1TDP1THRB | |
| SCHEMBL4759903 | 0.82 | ALDH1A1 (0.52) | KMT2AMAPTMEN1TDP1THRB | |
| SCHEMBL30024982 | 0.82 | ALDH1A1 (0.52) | KMT2AMAPTMEN1TDP1THRB | |
| SCHEMBL5078313 | 0.82 | POLB (0.57) | KMT2AMAPTMEN1TDP1THRB | |
| SCHEMBL710634 | 0.82 | KMT2A (0.63) | KMT2AMAPTMEN1TDP1THRB | |
| SCHEMBL9645846 | 0.80 | POLB (0.63) | KMT2AMAPTMEN1TDP1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4556706-A | Heavy metal-containing formazane dyes containing a fiber-reactive fluorotriazine group | CIBA GEIGY CORPORATION (US) | 1985-12-03 | — | — | US | disclosed |