Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 2/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1448415 | 0.83 | CCR2 (0.33) | CCR2PTGS2L3MBTL1 | |
| SCHEMBL6199512 | 0.80 | L3MBTL1 (0.33) | L3MBTL1 | |
| SCHEMBL4574416 | 0.79 | CA2 (0.34) | PTGS2 | |
| SCHEMBL8901063 | 0.79 | TET2 (0.33) | — | |
| SCHEMBL28186807 | 0.79 | ALDH1A1 (0.40) | — | |
| SCHEMBL27952384 | 0.75 | HSD11B1 (0.33) | CCR2L3MBTL1 | |
| SCHEMBL28938509 | 0.75 | CA1 (0.34) | L3MBTL1 | |
| SCHEMBL442816 | 0.72 | HSD11B1 (0.33) | CCR2PTGS2L3MBTL1 | |
| SCHEMBL1448807 | 0.72 | L3MBTL1 (0.44) | L3MBTL1 | |
| SCHEMBL1791418 | 0.72 | SMN1; SMN2 (0.50) | L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114933585-A | Therapeutically active compounds and methods of use thereof | 法国施维雅药厂 | 2022-08-23 | — | — | CN | disclosed |
| CN-108026067-B | 6-amino-quinoline-3-carbonitriles as COT modulators | 吉利德科学公司 | 2021-01-12 | — | — | CN | disclosed |
| CN-106715413-B | piperazine derivatives as liver X receptor modulators | VITAE PHARMACEUTICALS, INC. (US) | 2019-11-01 | — | — | CN | disclosed |
| CN-106458955-B | Aryl substituted heterocyclyl sulfones | 格吕伦塔尔有限公司 | 2019-07-19 | — | — | CN | disclosed |
| CN-106029076-B | Benzo piperazine composition as BET bromine domain inhibitor | 福马疗法公司 | 2019-06-07 | — | — | CN | disclosed |
| CN-108558889-A | Bu Luomo structural domain inhibitor | 赛尔基因昆蒂赛尔研究公司 | 2018-09-21 | — | — | CN | disclosed |
| CN-108558871-A | Novel tricyclic compound as anticancer agent | 百时美施贵宝公司 | 2018-09-21 | — | — | CN | disclosed |
| CN-106029663-B | Tricyclic compounds as anticancer agents | 百时美施贵宝公司 | 2018-06-01 | — | — | CN | disclosed |
| CN-106715413-A | Piperazine derivatives as liver x receptor modulators | 生命医药公司 | 2017-05-24 | — | — | CN | disclosed |
| CN-104919613-A | Delta-olefin oligomers and polymers and their use as hole-conducting materials | BASF SE | 2015-09-16 | — | — | CN | disclosed |
| CN-102057015-B | Chlorinated naphthalenetetracarboxylic acid derivatives, preparation thereof and use thereof in organic electronics | BASF SE | 2015-07-22 | — | — | CN | disclosed |