SCHEMBL28017334

SCHEMBL28017334

CCc1c(O)ccc2[nH]ccc12

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
P2RX7 Q99572 1/20 0.41
MTNR1A P48039 1/20 0.39
MTNR1B P49286 1/20 0.39
ESR1 P03372 4/20 0.39
ESR2 Q92731 4/20 0.39
ALDH1A1 P00352 2/20 0.35
PKM P14618 1/20 0.35
GAA P10253 2/20 0.34
AHR P35869 1/20 0.34
USP2 O75604 1/20 0.34
ALOX15 P16050 1/20 0.34
RAD51 Q06609 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
KDM4E B2RXH2 1/20 0.34
GLA P06280 1/20 0.34
HPGD P15428 1/20 0.34
CASP1 P29466 1/20 0.34
CASP7 P55210 1/20 0.34
HSD17B10 Q99714 1/20 0.34
P4HB P07237 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31543744 1.00 P2RX7 (0.41) P2RX7MTNR1AMTNR1BESR1ESR2
SCHEMBL1400453 0.85 MTNR1A (0.40) P2RX7MTNR1AMTNR1BALDH1A1PKM
SCHEMBL4623327 0.80 ALDH1A1 (0.53) MTNR1AMTNR1BALDH1A1PKMGAA
SCHEMBL14008515 0.77 RHEB (0.44) P2RX7MTNR1AMTNR1BAHR
SCHEMBL2984606 0.77 P2RX7 (0.39) P2RX7MTNR1AMTNR1BAHRPARP1
SCHEMBL10262821 0.77 P2RX7 (0.41) P2RX7MTNR1AMTNR1BAHRPARP1
SCHEMBL1400229 0.77 SRD5A1 (0.40) MTNR1AMTNR1BALDH1A1GAAAHR
SCHEMBL30026897 0.76 TRPA1 (0.48) ESR1ESR2ALDH1A1GAAKDM4E
SCHEMBL858277 0.76 TRPA1 (0.48) ESR1ESR2ALDH1A1GAAKDM4E
SCHEMBL15797416 0.75 P2RX7 (0.52) P2RX7MTNR1AMTNR1BNPSR1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104974848-B White Galaxy extract and its extracting process and application 河南红枫种苗股份有限公司 2018-05-08 CN claimed
CN-105112158-B White Galaxy extract and preparation method and application 河南红枫种苗股份有限公司 2018-04-06 CN claimed
CN-105001989-B White Galaxy essential oil and preparation method and application 河南红枫种苗股份有限公司 2018-04-06 CN claimed
CN-105112158-A Euonymus japonicus Thunb. extract and its preparation method and use HENAN HONGFENG SEED CO LTD 2015-12-02 CN claimed
CN-105001989-A Euonymus japonicus essential oil and preparing method and application thereof HENAN HONGFENG SEED CO LTD 2015-10-28 CN claimed
CN-104974848-A Xuezhonghong extract, and extraction method and application thereof HENAN HONGFENG SEED CO LTD 2015-10-14 CN claimed
CN-118420512-A Benzoyl glycine derivative, and preparation method and application thereof 中国药科大学 2024-08-02 CN disclosed
CN-104974848-B White Galaxy extract and its extracting process and application 河南红枫种苗股份有限公司 2018-05-08 CN disclosed
CN-105112158-B White Galaxy extract and preparation method and application 河南红枫种苗股份有限公司 2018-04-06 CN disclosed
CN-105001989-B White Galaxy essential oil and preparation method and application 河南红枫种苗股份有限公司 2018-04-06 CN disclosed
CN-105112158-A Euonymus japonicus Thunb. extract and its preparation method and use HENAN HONGFENG SEED CO LTD 2015-12-02 CN disclosed
CN-105001989-A Euonymus japonicus essential oil and preparing method and application thereof HENAN HONGFENG SEED CO LTD 2015-10-28 CN disclosed
CN-104974848-A Xuezhonghong extract, and extraction method and application thereof HENAN HONGFENG SEED CO LTD 2015-10-14 CN disclosed