Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.33 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | BDKRB2 | P30411 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28824086 | 0.86 | NPC1 (0.42) | NPC1RAB9ASLC2A1L3MBTL1BDKRB2 | |
| SCHEMBL8973155 | 0.82 | HRH3 (0.45) | LMNAALDH1A1TDP1SLC2A1L3MBTL1 | |
| SCHEMBL8973238 | 0.82 | SLC6A2 (0.45) | TSHRLMNACYP2C9CYP2C19TDP1 | |
| SCHEMBL27647959 | 0.80 | CYP1A2 (0.37) | CYP3A4LMNACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL28429634 | 0.80 | HTR7 (0.39) | LMNAPSMD14MAPK1MEN1KMT2A | |
| SCHEMBL28771687 | 0.80 | BDKRB2 (0.40) | TSHRLMNAALDH1A1TDP1SLC2A1 | |
| SCHEMBL9016030 | 0.80 | ESR1 (0.47) | MAPTCYP3A4LMNACYP1A2CYP2C9 | |
| SCHEMBL8101640 | 0.79 | CYP19A1 (0.47) | MAPTTSHRCYP3A4LMNACYP1A2 | |
| SCHEMBL12112001 | 0.79 | CYP19A1 (0.47) | MAPTTSHRCYP3A4LMNACYP1A2 | |
| SCHEMBL1374200 | 0.79 | POLB (0.45) | MAPTTSHRLMNAALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104678028-A | Pretreatment and detection method for biogen amine neurotransmitter and detection kit | INST PHARM & TOXICOLOGY AMMS | 2015-06-03 | — | — | CN | claimed |
| CN-104678028-B | The pre-treatment of biological original amine neurotransmitters and detection method and detection kit | 中国人民解放军军事医学科学院毒物药物研究所 | 2017-08-15 | — | — | CN | disclosed |
| CN-104678028-A | Pretreatment and detection method for biogen amine neurotransmitter and detection kit | INST PHARM & TOXICOLOGY AMMS | 2015-06-03 | — | — | CN | disclosed |