Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 3/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29034259 | 0.78 | REN (0.38) | REN | |
| SCHEMBL27513742 | 0.73 | DRD2 (0.36) | SLC6A3TAAR1 | |
| SCHEMBL28029236 | 0.72 | ADRA2C (0.52) | SLC6A3 | |
| SCHEMBL8218635 | 0.71 | TAAR1 (0.44) | SLC6A3TAAR1 | |
| SCHEMBL28666083 | 0.70 | DRD2 (0.50) | — | |
| SCHEMBL28010292 | 0.70 | DRD2 (0.42) | SLC6A3TAAR1 | |
| SCHEMBL28105993 | 0.69 | DRD2 (0.42) | — | |
| SCHEMBL28018712 | 0.68 | FAAH (0.39) | RENSLC6A3 | |
| SCHEMBL2388114 | 0.68 | MEN1 (0.41) | — | |
| SCHEMBL28860435 | 0.68 | DRD2 (0.41) | SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104710385-A | PDE10 inhibitors and related compositions and methods | OMEROS CORP | 2015-06-17 | — | — | CN | disclosed |