Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 1/20 | 0.48 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.43 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.43 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.41 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.41 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.41 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28019664 | 0.87 | GRIN1 (0.48) | HRH3CYP2D6GRIN1GRIN2BSPHK1 | |
| SCHEMBL2476770 | 0.84 | YAP1 (0.52) | GHSR | |
| SCHEMBL2478075 | 0.83 | SGMS2 (0.50) | HRH3SGMS2SMN1; SMN2 | |
| SCHEMBL2475047 | 0.83 | PDE4B (0.46) | GHSRPDE4BGRIN1GRIN2BKDM2B | |
| SCHEMBL16564510 | 0.82 | HTR1A (0.48) | HRH3GRIN1GRIN2BSPHK1SPHK2 | |
| SCHEMBL2475650 | 0.80 | ALDH1A1 (0.56) | SMN1; SMN2 | |
| SCHEMBL3354512 | 0.79 | ALDH1A1 (0.57) | SPHK1SPHK2TP53SMN1; SMN2 | |
| SCHEMBL3356183 | 0.77 | ALDH1A1 (0.54) | SPHK1SPHK2TP53SMN1; SMN2 | |
| SCHEMBL2478613 | 0.76 | GHSR (0.49) | GHSRKDM2B | |
| SCHEMBL13504469 | 0.75 | GRIN1 (0.43) | HRH3CYP2D6GRIN1GRIN2BSPHK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104666299-A | 4-(azacycloalkyl)benzene-1,3-diol compounds as tyrosinase inhibitors, process for the preparation thereof and use thereof | GALDERMA RES & DEV | 2015-06-03 | — | — | CN | disclosed |