Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.38 |
| ▸ | ALDH1A3 | P47895 | 2/20 | 0.37 |
| ▸ | CSF1R | P07333 | 4/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MMP1 | P03956 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10288508 | 0.72 | ALDH1A1 (0.53) | MAPTALDH1A3NPSR1L3MBTL1GAA | |
| SCHEMBL23847671 | 0.67 | ALDH1A1 (0.55) | MAPTCSF1RL3MBTL1GAAALDH1A1 | |
| SCHEMBL17805391 | 0.67 | NPSR1 (0.44) | MAPTCSF1RNPSR1L3MBTL1GAA | |
| SCHEMBL24383692 | 0.67 | ALDH1A1 (0.49) | MAPTALDH1A3CSF1RNPSR1L3MBTL1 | |
| SCHEMBL28020109 | 0.64 | NPC1 (0.59) | MAPTKDM4CL3MBTL1GAAALDH1A1 | |
| SCHEMBL22523017 | 0.62 | ALDH1A1 (0.46) | MAPTALDH1A3NPSR1GAAALDH1A1 | |
| SCHEMBL19152187 | 0.62 | ALDH1A3 (0.49) | MAPTALDH1A3NPSR1L3MBTL1GAA | |
| SCHEMBL2320267 | 0.62 | ALDH1A1 (0.58) | MAPTNPSR1L3MBTL1GAAALDH1A1 | |
| SCHEMBL5543471 | 0.61 | MAPK1 (0.51) | MAPTCSF1RNPSR1GAAALDH1A1 | |
| SCHEMBL4468998 | 0.61 | ADRB1 (0.51) | MAPTALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104829592-A | Synthesis method of 4-piperidyl-1H-pyrrole-3-formamide compound hydrochloride | 1ST AFFILIATED HOSPITAL HENAN UNIV SCIENCE & TECHNOLOGY | 2015-08-12 | — | — | CN | disclosed |
| CN-104829592-A | Synthesis method of 4-piperidyl-1H-pyrrole-3-formamide compound hydrochloride | 1ST AFFILIATED HOSPITAL HENAN UNIV SCIENCE & TECHNOLOGY | 2015-08-12 | — | — | CN | disclosed |