Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.40 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21049522 | 0.73 | KEAP1 (0.41) | SMN1; SMN2KEAP1KDM4EALDH1A1 | |
| SCHEMBL18230673 | 0.70 | KEAP1 (0.43) | SMN1; SMN2KEAP1KDM4EALDH1A1 | |
| SCHEMBL342075 | 0.65 | SMN1; SMN2 (0.40) | SMN1; SMN2KEAP1KDM4EGAAALDH1A1 | |
| SCHEMBL8560109 | 0.64 | KEAP1 (0.83) | SMN1; SMN2KEAP1KDM4EGAAALDH1A1 | |
| SCHEMBL5988693 | 0.64 | KEAP1 (0.83) | SMN1; SMN2KEAP1KDM4EGAAALDH1A1 | |
| SCHEMBL5903339 | 0.64 | KEAP1 (0.83) | SMN1; SMN2KEAP1KDM4EGAAALDH1A1 | |
| SCHEMBL3200530 | 0.64 | KEAP1 (0.83) | SMN1; SMN2KEAP1KDM4EGAAALDH1A1 | |
| SCHEMBL1703703 | 0.64 | KEAP1 (0.83) | SMN1; SMN2KEAP1KDM4EGAAALDH1A1 | |
| SCHEMBL15512227 | 0.64 | KDM4E (0.36) | SMN1; SMN2KEAP1KDM4EGAAALDH1A1 | |
| SCHEMBL28301264 | 0.63 | MEN1 (0.35) | SMN1; SMN2KEAP1KDM4EGAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112533972-A | Polyurethane compositions with low content of monomeric diisocyanates | SIKA技术股份公司 | 2021-03-19 | — | — | CN | disclosed |
| CN-104640894-A | Two-component polyurethane composition | SIKA TECHNOLOGY AG | 2015-05-20 | — | — | CN | disclosed |