Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 3/20 | 0.56 |
| ▸ | FDPS | P14324 | 1/20 | 0.49 |
| ▸ | FGFR1 | P11362 | 9/20 | 0.47 |
| ▸ | FGFR4 | P22455 | 9/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.47 |
| ▸ | FLT4 | P35916 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | PI4KA | P42356 | 1/20 | 0.42 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.42 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.42 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.42 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.39 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.39 |
| ▸ | CDK2 | P24941 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6805557 | 0.87 | P2RX7 (0.48) | P2RX7FDPSFGFR1FGFR4HDAC6 | |
| SCHEMBL9435719 | 0.84 | PI4KA (0.62) | KDRPI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL22412661 | 0.83 | P2RX7 (0.55) | P2RX7HDAC6CCNE2CCNE1CDK2 | |
| SCHEMBL28020916 | 0.80 | P2RX7 (0.64) | P2RX7FDPSFGFR1FGFR4HDAC6 | |
| SCHEMBL4640082 | 0.79 | FGFR1 (0.47) | P2RX7FDPSFGFR1FGFR4HDAC6 | |
| SCHEMBL9544785 | 0.79 | FPR2 (0.37) | P2RX7HDAC6KDRCCNE2CCNE1 | |
| SCHEMBL23885424 | 0.79 | P2RX7 (0.66) | P2RX7FDPSFGFR1FGFR4HDAC6 | |
| SCHEMBL30254206 | 0.79 | P2RX7 (0.53) | P2RX7FDPSFGFR1FGFR4HDAC6 | |
| SCHEMBL30015306 | 0.78 | FPR2 (0.43) | P2RX7HDAC6CCNE2CCNE1CDK2 | |
| SCHEMBL23558005 | 0.78 | FPR2 (0.43) | P2RX7HDAC6CCNE2CCNE1CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230159536-A1 | PYRROLOPYRIMIDINE AMINES AS COMPLEMENT INHIBITORS | WILMINGTON TRUST, NATIONAL ASSOCIATION | 2023-05-25 | — | — | US | disclosed |
| US-20230159536-A1 | PYRROLOPYRIMIDINE AMINES AS COMPLEMENT INHIBITORS | WILMINGTON TRUST, NATIONAL ASSOCIATION | 2023-05-25 | — | — | US | disclosed |
| US-20230159536-A1 | PYRROLOPYRIMIDINE AMINES AS COMPLEMENT INHIBITORS | WILMINGTON TRUST, NATIONAL ASSOCIATION | 2023-05-25 | — | — | US | disclosed |
| CN-115427044-A | Pyrrolopyrimidines as complement inhibitors | 拜奥克里斯特制药公司 | 2022-12-02 | — | — | CN | disclosed |
| US-20210163484-A1 | METHOD FOR SYNTHESIZING DIVERSELY SUBSTITUTED PURINES | UNIVERSITÉ GRENOBLE ALPES (FR) | 2021-06-03 | — | — | US | disclosed |
| WO-1993018035-A1 | ANGIOTENSIN II RECEPTOR ANTAGONISTS | ABBOTT LABORATORIES (US) | 1993-09-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210163484-A1 | METHOD FOR SYNTHESIZING DIVERSELY SUBSTITUTED PURINES | PNP, UMPS, NUDT1 | P2RX7 144/4885FDPS 25/4885FGFR1 981/4885 |
| US-20230159536-A1 | PYRROLOPYRIMIDINE AMINES AS COMPLEMENT INHIBITORS | C5, C9, C1QBP | P2RX7 659/4885FDPS 120/4885FGFR1 3786/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.